GENR
{
RETE|ID 1 PFgn0004084	CLA 1 gene array ; SO:0005851	GSYM 1 &agr;&ggr;-element	DT 1 30 Oct 06	RESZ 476	CLOC 1 87C1	REF 1	
GSYM|&agr;&ggr;-element
ID|PFgn0004084
CLA|gene_array ; SO:0005851
|nuclear_gene ; SO:0000087
|non_protein_coding_gene ; SO:0000011
|gene_array ; SO:0005851
|non_protein_coding_gene ; SO:0000011
|nuclear_gene ; SO:0000087
KLOC|111048
CLOC|87C1
|Left limit from molecular mapping relative to Hsp70Ba (FBrf0035243)
|Right limit from molecular mapping relative to Hsp70Bc (FBrf0035243)
DT|30 Oct 06
REF
{
REFM|FBrf0190734
|Kotlikova et al.
|2006
|0
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0052865	CLA 1 non protein coding gene ; SO:0000011	GSYM 1 &agr;&ggr;-element:CR32865	DT 1 30 Oct 06	RESZ 377	CLOC 1 87B13	
GSYM|&agr;&ggr;-element:CR32865
ID|PFgn0052865
CLA|non_protein_coding_gene ; SO:0000011
|nuclear_gene ; SO:0000087
|member_gene_array ; SO:0000081
|non_protein_coding_gene ; SO:0000011
|nuclear_gene ; SO:0000087
KLOC|110988
CLOC|87B13
|Limits computationally determined from genome sequence between @P{PZ}svp<up>07842</up>@ and @P{lacW}Vha55<up>j2E9</up>@
DT|30 Oct 06
}
# EOR
GENR
{
RETE|ID 1 PFgn0015567	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;-Adaptin	DT 1 30 Oct 06	RESZ 3797	PDOM 2 INTERPRO:IPR003164 == AP2 clathrin adaptin, alpha chain, C-terminal	FNC 4 asymmetric cell division	CEL 1 plasma membrane	CLOC 1 21C2	ALESR 3	REF 13	
GSYM|&agr;-Adaptin
ID|PFgn0015567
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|30250
CLOC|21C2
|Limits computationally determined from genome sequence between @P{lacW}RpI135<up>k16513</up>@&@P{lacW}ebi<up>k16213</up>@ and @P{lacW}l(2)k09610<up>k09610</up>@&@P{lacW}S<up>k09538a</up>@
PDOM|IPR003164 == AP2 clathrin adaptin, alpha chain, C-terminal
|IPR009028 == AP2 clathrin adaptor, alpha and beta chain, appendage
FNC|asymmetric cell division ; GO:0008356 | traceable author statement
|synaptic vesicle coating ; GO:0016183 | traceable author statement
|synaptic vesicle transport ; GO:0048489 | traceable author statement
|vesicle coating ; GO:0006901 | traceable author statement
ENZ|binding ; GO:0005488 | inferred from electronic annotation
CEL|plasma membrane ; GO:0005886 | inferred from direct assay
DT|30 Oct 06
REV|FBrf0141528
|FBrf0148996
REF
{
REFM|FBrf0101995
|Rorth et al.
|1998
|-1
REFM|FBrf0111489
|Spradling et al.
|1999
|-1
REFM|FBrf0187299
|Bhalerao et al.
|2005
|0
REFM|FBrf0135708
|Kraut et al.
|2001
|-1
REFM|FBrf0067338
|BDGP Project Members
|1994-1999
|-1
REFM|-1147191020
|Polo
|2006
|0
|Cell 124: 897--900
REFM|FBrf0132177
|Gene Disruption Project members
|2001-
|-1
REFM|FBrf0135968
|Kraut et al.
|2001
|-1
REFM|FBrf0093110
|Gonzalez-Gaitan and Jackle
|1997
|-1
REFM|FBrf0191527
|Crosetto
|2005
|0
REFM|FBrf0094735
|Forjanic et al.
|1997
|-1
REFM|FBrf0189339
|Verstreken and Bellen
|2006
|0
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|0
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
FNC|intracellular protein transport ; GO:0006886 | inferred from electronic annotation
|protein complex assembly ; GO:0006461 | inferred from electronic annotation
ENZ|binding ; GO:0005488 | inferred from electronic annotation
|structural molecule activity ; GO:0005198 | inferred from electronic annotation
CEL|clathrin coat of trans-Golgi network vesicle ; GO:0030130 | inferred from electronic annotation
}

REFDSR
{
RDID|FBrf0191527
|Crosetto
|2005
SYN|AP2
}

ALESR
{
ASYM|&agr;-Adaptin<up>06694</up>
ID|PFal0008113
TRN|FBti0004442 == P{PZ}&agr;-Adaptin<up>06694</up>
REF|FBrf0067338
|FBrf0094735
|FBrf0093110
|FBrf0111489
REFDSR
{
RDID|FBrf0067338
|BDGP Project Members
|1994-1999
TRN|FBti0004442 == P{PZ}&agr;-Adaptin<up>06694</up>
}

REFDSR
{
RDID|FBrf0093110
|Gonzalez-Gaitan and Jackle
|1997
TRN|FBti0004442 == P{PZ}&agr;-Adaptin<up>06694</up>
}

REFDSR
{
RDID|FBrf0094735
|Forjanic et al.
|1997
TRN|FBti0004442 == P{PZ}&agr;-Adaptin<up>06694</up>
}

REFDSR
{
RDID|FBrf0111489
|Spradling et al.
|1999
TRN|FBti0004442 == P{PZ}&agr;-Adaptin<up>06694</up>
}

}

ALESR
{
ASYM|&agr;-Adaptin<up>EP2519</up>
ID|PFal0089856
REF|FBrf0132177
|FBrf0101995
REFDSR
{
RDID|FBrf0101995
|Rorth et al.
|1998
TRN|FBti0010425 == P{EP}&agr;-Adaptin<up>EP2519</up>
}

REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0010425 == P{EP}&agr;-Adaptin<up>EP2519</up>
}

}

ALESR
{
ASYM|&agr;-Adaptin<up>EP896</up>
ID|PFal0123350
REF|FBrf0132177
|FBrf0135708
|FBrf0135968
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0007726 == P{EP}&agr;-Adaptin<up>EP896</up>
}

REFDSR
{
RDID|FBrf0135708
|Kraut et al.
|2001
TRN|FBti0007726 == P{EP}&agr;-Adaptin<up>EP896</up>
}

REFDSR
{
RDID|FBrf0135968
|Kraut et al.
|2001
TRN|FBti0007726 == P{EP}&agr;-Adaptin<up>EP896</up>
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0010215	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;-Cat	DT 1 30 Oct 06	RESZ 3151	PDOM 1 INTERPRO:IPR008731 == phosphotransferase system, PEP-utilising enzyme, N-terminal	FNC 2 cytoskeletal anchoring	CEL 1 catenin complex	CLOC 1 80F1--2	ALESR 1	REF 11	
GSYM|&agr;-Cat
ID|PFgn0010215
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|101306-2605
CLOC|80F1--2
|Limits computationally determined from genome sequence between @P{lacW}l(3)j1B10<up>j1B10</up>@ and @P{lacW}l(3)j2C4<up>j2C4</up>@
PDOM|IPR008731 == phosphotransferase system, PEP-utilising enzyme, N-terminal
FNC|cytoskeletal anchoring ; GO:0007016 | inferred from sequence or structural similarity
|oocyte localization during oogenesis ; GO:0030720 | traceable author statement
ENZ|actin binding ; GO:0003779 | inferred from sequence or structural similarity
|cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity
CEL|catenin complex ; GO:0016342 | inferred from sequence or structural similarity
DT|30 Oct 06
REV|FBrf0155643
|FBrf0155680
REF
{
REFM|FBrf0132100
|Goldstein and Gunawardena
|2000
|-1
REFM|FBrf0188763
|Drosophila Heterochromatin Genome Project
|2006
|-1
REFM|FBrf0187316
|Lecuit
|2005
|-1
REFM|FBrf0191566
|Davies
|2005
|-1
REFM|FBrf0167770
|Grevengoed et al.
|2003
|-1
REFM|FBrf0129868
|Hynes and Zhao
|2000
|-1
REFM|-761870240
|Montell
|2006
|-1
|Curr. Opin. Genet. Dev. 16: 374--383
REFM|FBrf0187462
|Grzeschik and Knust
|2005
|-1
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0187401
|Woolner et al.
|2005
|-1
REFM|FBrf0151270
|Magie et al.
|2002
|-1
}

REFDSR
{
RDID|FBrf0129868
|Hynes and Zhao
|2000
FNC|cytoskeletal anchoring ; GO:0007016 | inferred from sequence or structural similarity
CEL|catenin complex ; GO:0016342 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0132100
|Goldstein and Gunawardena
|2000
ENZ|actin binding ; GO:0003779 | inferred from sequence or structural similarity
|cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0151270
|Magie et al.
|2002
WTI|Rho1 (data from @&agr;-Cat<up>Scer\UAS.P\T.cMa</up>@)
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
FNC|phosphoenolpyruvate-dependent sugar phosphotransferase system ; GO:0009401 | inferred from electronic annotation
ENZ|phosphoenolpyruvate-protein phosphotransferase activity ; GO:0008965 ; EC:2.7.3.9 | inferred from electronic annotation
|sugar porter activity ; GO:0005351 | inferred from electronic annotation
CEL|actin cytoskeleton ; GO:0015629 | inferred from electronic annotation
|cytoplasm ; GO:0005737 | inferred from electronic annotation
}

ALESR
{
ASYM|&agr;-Cat<up>Scer\UAS.T:Avic\GFP-sg</up>
ID|PFal0095916
REF|FBrf0187401
REFDSR
{
RDID|FBrf0187401
|Woolner et al.
|2005
CNS|FBtp0010647 == P{UAS-&agr;-Cat.T:GFP.sg}
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0015568	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;-Est1	DT 1 30 Oct 06	RESZ 995	CLOC 1 84D9	REF 3	
GSYM|&agr;-Est1
ID|PFgn0015568
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|106052
CLOC|84D9
|Limits computationally determined from genome sequence between @P{EP}EP3060<up>EP3060</up>@ and @P{PZ}grn<up>05930</up>@
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|-1032776461
|Hollien
|2006
|-1
|Science 313: http://www.sciencemag.org/cgi/content/full/313/5783/104/DC1
REFM|FBrf0191437
|Gerber et al.
|2006
|-1
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity with EMBL:AF064523
}

REFDSR
{
RDID|FBrf0191437
|Gerber et al.
|2006
SYN|CG1031
}

REFDSR
{
RDID|-1032776461
|Hollien
|2006
SYN|CG1031
|alpha-Est1
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0015569	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;-Est10	DT 1 30 Oct 06	RESZ 1146	CLOC 1 84D8--9	REF 3	
GSYM|&agr;-Est10
ID|PFgn0015569
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|106038-12394
CLOC|84D8--9
|Limits computationally determined from genome sequence between @P{EP}EP3060<up>EP3060</up>@ and @P{PZ}grn<up>05930</up>@
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0104946
|FlyBase
|1996-
|-1
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
}

REFDSR
{
RDID|FBrf0104946
|FlyBase
|1996-
AM|Source for merge of: &agr;-Est10 anon-WO0172774.144
|Source for merge of &agr;-Est10 anon-WO0172774.144 was sequence comparison
|(date:051113).
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity with EMBL:AF133341; protein_id:AAD29685.1
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
ENZ|cholinesterase activity ; GO:0004104 ; EC:3.1.1.8 | inferred from electronic annotation
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0015570	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;-Est2	DT 1 30 Oct 06	RESZ 898	PDOM 1 INTERPRO:IPR000997 == Cholinesterase	CLOC 1 84D9	REF 2	
GSYM|&agr;-Est2
ID|PFgn0015570
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|106052
CLOC|84D9
|Limits computationally determined from genome sequence between @P{EP}EP3060<up>EP3060</up>@ and @P{PZ}grn<up>05930</up>@
PDOM|IPR000997 == Cholinesterase
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity with UniProt:P16854
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
ENZ|cholinesterase activity ; GO:0004104 ; EC:3.1.1.8 | inferred from electronic annotation
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0015571	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;-Est3	DT 1 30 Oct 06	RESZ 608	CLOC 1 84D9	REF 1	
GSYM|&agr;-Est3
ID|PFgn0015571
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|106052
CLOC|84D9
|Limits computationally determined from genome sequence between @P{EP}EP3060<up>EP3060</up>@ and @P{PZ}grn<up>05930</up>@
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity with UniProt:P16854
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0015572	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;-Est4	DT 1 30 Oct 06	RESZ 607	CLOC 1 84D9	REF 1	
GSYM|&agr;-Est4
ID|PFgn0015572
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|106052
CLOC|84D9
|Limits computationally determined from genome sequence between @P{EP}EP3060<up>EP3060</up>@ and @P{PZ}grn<up>05930</up>@
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity with EMBL:AF133341
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0027934	CLA 1 nuclear gene ; SO:0000087	GSYM 1 &agr;-Est4a&PSgr;	DT 1 30 Oct 06	RESZ 291	CLOC 1 84D9	
GSYM|&agr;-Est4a&PSgr;
ID|PFgn0027934
CLA|nuclear_gene ; SO:0000087
|pseudogene_attribute ; SO:0000042
|nuclear_gene ; SO:0000087
KLOC|106052
CLOC|84D9
|Limits computationally determined from genome sequence between @P{EP}EP3060<up>EP3060</up>@ and @P{PZ}grn<up>05930</up>@
DT|30 Oct 06
}
# EOR
GENR
{
RETE|ID 1 PFgn0015573	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;-Est5	DT 1 30 Oct 06	RESZ 851	CLOC 1 84D9	ALESR 1	REF 2	
GSYM|&agr;-Est5
ID|PFgn0015573
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|106052
CLOC|84D9
|Limits computationally determined from genome sequence between @P{EP}EP3060<up>EP3060</up>@ and @P{PZ}grn<up>05930</up>@
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0132177
|Gene Disruption Project members
|2001-
|-1
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity with EMBL:AF133341
}

ALESR
{
ASYM|&agr;-Est5<up>KG01079</up>
ID|PFal0131828
REF|FBrf0132177
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0021174 == P{SUPor-P}&agr;-Est5<up>KG01079</up>
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0015574	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;-Est6	DT 1 30 Oct 06	RESZ 607	CLOC 1 84D9	REF 1	
GSYM|&agr;-Est6
ID|PFgn0015574
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|106052
CLOC|84D9
|Limits computationally determined from genome sequence between @P{EP}EP3060<up>EP3060</up>@ and @P{PZ}grn<up>05930</up>@
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity with EMBL:AF133341
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0015575	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;-Est7	DT 1 30 Oct 06	RESZ 755	FNC 1 biological process unknown	CEL 1 cellular component unknown	CLOC 1 84D9	REF 1	
GSYM|&agr;-Est7
ID|PFgn0015575
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|106052
CLOC|84D9
|Limits computationally determined from genome sequence between @P{EP}EP3060<up>EP3060</up>@ and @P{PZ}grn<up>05930</up>@
FNC|biological process unknown ; GO:0000004 | no biological data available
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity
CEL|cellular component unknown ; GO:0008372 | no biological data available
DT|30 Oct 06
REF
{
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity with EMBL:AF133341
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0015576	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;-Est8	DT 1 30 Oct 06	RESZ 607	CLOC 1 84D9	REF 1	
GSYM|&agr;-Est8
ID|PFgn0015576
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|106052
CLOC|84D9
|Limits computationally determined from genome sequence between @P{EP}EP3060<up>EP3060</up>@ and @P{PZ}grn<up>05930</up>@
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity with EMBL:AF133341
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0015577	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;-Est9	DT 1 30 Oct 06	RESZ 866	CLOC 1 84D9	REF 2	
GSYM|&agr;-Est9
ID|PFgn0015577
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|106052
CLOC|84D9
|Limits computationally determined from genome sequence between @P{EP}EP3060<up>EP3060</up>@ and @P{PZ}grn<up>05930</up>@
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
ENZ|carboxylesterase activity ; GO:0004091 ; EC:3.1.1.1 | inferred from sequence or structural similarity with EMBL:AF133341
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
ENZ|cholinesterase activity ; GO:0004104 ; EC:3.1.1.8 | inferred from electronic annotation
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0022719	CLA 1 gene ; SO:0000704	GSYM 1 &agr;-Glu-2	DT 1 30 Oct 06	RESZ 79	
GSYM|&agr;-Glu-2
ID|PFgn0022719
CLA|gene ; SO:0000704
DT|30 Oct 06
}
# EOR
GENR
{
RETE|ID 1 PFgn0022718	CLA 1 gene ; SO:0000704	GSYM 1 &agr;-Glu-3	DT 1 30 Oct 06	RESZ 79	
GSYM|&agr;-Glu-3
ID|PFgn0022718
CLA|gene ; SO:0000704
DT|30 Oct 06
}
# EOR
GENR
{
RETE|ID 1 PFgn0022717	CLA 1 gene ; SO:0000704	GSYM 1 &agr;-Glu-4	DT 1 30 Oct 06	RESZ 79	
GSYM|&agr;-Glu-4
ID|PFgn0022717
CLA|gene ; SO:0000704
DT|30 Oct 06
}
# EOR
GENR
{
RETE|ID 1 PFgn0022716	CLA 1 gene ; SO:0000704	GSYM 1 &agr;-Man-4	DT 1 30 Oct 06	RESZ 79	
GSYM|&agr;-Man-4
ID|PFgn0022716
CLA|gene ; SO:0000704
DT|30 Oct 06
}
# EOR
GENR
{
RETE|ID 1 PFgn0010338	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;-Man-I	DT 1 30 Oct 06	RESZ 4304	FNC 2 protein amino acid N-linked glycosylation	CEL 2 Golgi apparatus	CLOC 1 9B5--7	ALESR 9	REF 6	
GSYM|&agr;-Man-I
ID|PFgn0010338
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|11836-8696
CLOC|9B5--7
|Limits computationally determined from genome sequence between @P{EP}nej<up>EP1149</up>@&@P{EP}nej<up>EP1179</up>@ and @P{EP}&agr;-Man-I<up>EP1628</up>@&@P{EP}&agr;-Man-I<up>EP1307</up>@
FNC|protein amino acid N-linked glycosylation ; GO:0006487 | inferred from sequence or structural similarity
|protein amino acid N-linked glycosylation ; GO:0006487 | non-traceable author statement
ENZ|mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571 ; EC:3.2.1.113 | inferred from sequence or structural similarity
CEL|Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity
|Golgi membrane ; GO:0000139 | non-traceable author statement
DT|30 Oct 06
REF
{
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0184340
|Gene Disruption Project members and Exelixis
|2005
|-1
REFM|FBrf0148886
|FlyBase Genome Annotators
|2002-2003
|-1
REFM|FBrf0132177
|Gene Disruption Project members
|2001-
|-1
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
REFM|FBrf0189446
|Wang et al.
|2006
|-1
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
FNC|protein amino acid N-linked glycosylation ; GO:0006487 | inferred from sequence or structural similarity with UniProt:O60476
ENZ|mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571 ; EC:3.2.1.113 | inferred from sequence or structural similarity with UniProt:O60476
CEL|Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with UniProt:O60476
}

REFDSR
{
RDID|FBrf0148886
|FlyBase Genome Annotators
|2002-2003
AM|Source for merge of: &agr;-Man-I CG18799
|Annotations CG17809, CG18799 merged as CG32684 in release 3 of the genome annotation.
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
ENZ|calcium ion binding ; GO:0005509 | inferred from electronic annotation
}

REFDSR
{
RDID|FBrf0189446
|Wang et al.
|2006
SYN|CG18799
}

ALESR
{
ASYM|&agr;-Man-I<up>EP1307</up>
ID|PFal0131558
REF|FBrf0132177
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0011850 == P{EP}&agr;-Man-I<up>EP1307</up>
}

}

ALESR
{
ASYM|&agr;-Man-I<up>EP1612</up>
ID|PFal0131557
REF|FBrf0132177
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0007526 == P{EP}&agr;-Man-I<up>EP1612</up>
}

}

ALESR
{
ASYM|&agr;-Man-I<up>EP1628</up>
ID|PFal0131556
REF|FBrf0132177
|FBrf0189446
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0007539 == P{EP}&agr;-Man-I<up>EP1628</up>
}

}

ALESR
{
ASYM|&agr;-Man-I<up>EP556</up>
ID|PFal0131555
REF|FBrf0132177
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0007323 == P{EP}&agr;-Man-I<up>EP556</up>
}

}

ALESR
{
ASYM|&agr;-Man-I<up>EP982</up>
ID|PFal0131554
REF|FBrf0132177
|FBrf0189446
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0007347 == P{EP}&agr;-Man-I<up>EP982</up>
}

}

ALESR
{
ASYM|&agr;-Man-I<up>KG00557</up>
ID|PFal0128268
REF|FBrf0132177
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0020934 == P{SUPor-P}&agr;-Man-I<up>KG00557</up>
}

}

ALESR
{
ASYM|&agr;-Man-I<up>KG03944</up>
ID|PFal0137613
REF|FBrf0132177
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0023423 == P{SUPor-P}&agr;-Man-I<up>KG03944</up>
}

}

ALESR
{
ASYM|&agr;-Man-I<up>KG04725</up>
ID|PFal0134362
REF|FBrf0132177
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0021867 == P{SUPor-P}&agr;-Man-I<up>KG04725</up>
}

}

ALESR
{
ASYM|&agr;-Man-I<up>d06998</up>
ID|PFal0188395
REF|FBrf0184340
REFDSR
{
RDID|FBrf0184340
|Gene Disruption Project members and Exelixis
|2005
AMIS|Separable from: @P{XP}CG13624<up>d06998</up>@.
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0011740	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;-Man-II	DT 1 30 Oct 06	RESZ 2218	FNC 2 protein amino acid N-linked glycosylation	CEL 1 Golgi membrane	CLOC 1 85D15--16	ALESR 1	REF 4	
GSYM|&agr;-Man-II
ID|PFgn0011740
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|107838-21809
CLOC|85D15--16
|Limits computationally determined from genome sequence between @P{lacW}l(3)L4092<up>L4092</up>@ and P{PZ}ps<up>10615</up>&@P{PZ}Ras85D<up>06677</up>@
FNC|protein amino acid N-linked glycosylation ; GO:0006487 | non-traceable author statement
|protein amino acid glycosylation ; GO:0006486 | inferred from sequence or structural similarity
ENZ|mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity ; GO:0004572 ; EC:3.2.1.114 | inferred from sequence or structural similarity
CEL|Golgi membrane ; GO:0000139 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0104946
|FlyBase
|1996-
|-1
REFM|FBrf0111467
|Rabouille et al.
|1999
|-1
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
}

REFDSR
{
RDID|FBrf0104946
|FlyBase
|1996-
AM|Source for merge of: &agr;-Man-II CG18802
|Source for merge of &agr;-Man-II CG18802 was sequence comparison (date:001104).
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
FNC|protein amino acid glycosylation ; GO:0006486 | inferred from sequence or structural similarity with UniProt:Q24451
ENZ|mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity ; GO:0004572 ; EC:3.2.1.114 | inferred from sequence or structural similarity with UniProt:Q24451
CEL|Golgi membrane ; GO:0000139 | inferred from sequence or structural similarity with MGD:Man2a1; MGI:MGI:104669
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
FNC|carbohydrate metabolism ; GO:0005975 | inferred from electronic annotation
|mannose metabolism ; GO:0006013 | inferred from electronic annotation
ENZ|alpha-mannosidase activity ; GO:0004559 ; EC:3.2.1.24 | inferred from electronic annotation
}

ALESR
{
ASYM|&agr;-Man-II<up>&Dgr;.MtnA.T:Ivir\HA1</up>
ID|PFal0101840
REF|FBrf0111467
REFDSR
{
RDID|FBrf0111467
|Rabouille et al.
|1999
OTH|Carried in plasmid "&Dgr;dGMII-HA<down>3</down>" and transfected into S2 cells.
|The subcellular location of the protein has been studied.
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0026616	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;-Man-IIb	DT 1 30 Oct 06	RESZ 1977	FNC 3 carbohydrate metabolism	CEL 1 Golgi membrane	CLOC 1 89A5	ALESR 1	REF 3	
GSYM|&agr;-Man-IIb
ID|PFgn0026616
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|113915
CLOC|89A5
|Limits computationally determined from genome sequence between @P{PZ}l(3)06536<up>06536</up>@ and @P{PZ}blp<up>01618</up>@
FNC|carbohydrate metabolism ; GO:0005975 | inferred from electronic annotation
|mannose metabolism ; GO:0006013 | inferred from electronic annotation
|protein secretion ; GO:0009306 | inferred from electronic annotation
ENZ|alpha-mannosidase activity ; GO:0004559 ; EC:3.2.1.24 | inferred from sequence or structural similarity
|mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity ; GO:0004572 ; EC:3.2.1.114 | inferred from sequence or structural similarity
CEL|Golgi membrane ; GO:0000139 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0132177
|Gene Disruption Project members
|2001-
|-1
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
ENZ|alpha-mannosidase activity ; GO:0004559 ; EC:3.2.1.24 | inferred from sequence or structural similarity with UniProt:P27046
|mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity ; GO:0004572 ; EC:3.2.1.114 | inferred from sequence or structural similarity with UniProt:P27046
CEL|Golgi membrane ; GO:0000139 | inferred from sequence or structural similarity with MGD:Man2a1; MGI:MGI:104669
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
FNC|carbohydrate metabolism ; GO:0005975 | inferred from electronic annotation
|mannose metabolism ; GO:0006013 | inferred from electronic annotation
|protein secretion ; GO:0009306 | inferred from electronic annotation
}

ALESR
{
ASYM|&agr;-Man-IIb<up>KG05078</up>
ID|PFal0134437
REF|FBrf0132177
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0021906 == P{SUPor-P}&agr;-Man-IIb<up>KG05078</up>
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0003470	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;-Spec	DT 1 30 Oct 06	RESZ 8785	PDOM 2 INTERPRO:IPR001452 == Src homology-3	FNC 1 cytoskeleton organization and biogenesis	CEL 2 cytoskeleton	CLOC 1 62B4	ALESR 5	REF 24	
GSYM|&agr;-Spec
ID|PFgn0003470
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|gene_with_dicistronic_primary_transcript ; SO:0000721
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|79745
CLOC|62B4
|Limits computationally determined from genome sequence between @P{EP}rho<up>EP3704</up>@&@P{PZ}l(3)06226<up>06226</up>@ and @P{PZ}dlt<up>04276</up>@
PDOM|IPR001452 == Src homology-3
|IPR013315 == Spectrin alpha chain
FNC|cytoskeleton organization and biogenesis ; GO:0007010 | inferred from sequence or structural similarity
ENZ|actin binding ; GO:0003779 | inferred from sequence or structural similarity
|calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity
|cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity
CEL|cytoskeleton ; GO:0005856 | inferred from sequence or structural similarity
|spectrin ; GO:0008091 | inferred from sequence or structural similarity
DT|30 Oct 06
REV|FBrf0132360
REF
{
REFM|FBrf0190715
|Delalle et al.
|2005
|-1
REFM|FBrf0148886
|FlyBase Genome Annotators
|2002-2003
|-1
REFM|FBrf0132100
|Goldstein and Gunawardena
|2000
|-1
REFM|FBrf0187454
|Chandrasekaran and Beckendorf
|2005
|-1
REFM|FBrf0092605
|Lee et al.
|1997
|-1
REFM|-1132180414
|Siddall
|2006
|-1
|Proc. Natl. Acad. Sci. USA 103: 8402--8407
REFM|FBrf0190309
|McClure and Schubiger
|2005
|-1
REFM|FBrf0187466
|Jin et al.
|2005
|-1
REFM|FBrf0067338
|BDGP Project Members
|1994-1999
|-1
REFM|FBrf0190507
|Grieder et al.
|2005
|-1
REFM|FBrf0187325
|Pielage et al.
|2005
|-1
REFM|FBrf0187387
|Kai et al.
|2005
|-1
REFM|FBrf0091300
|de Cuevas et al.
|1996
|-1
REFM|FBrf0188261
|Karlin et al.
|2005
|-1
REFM|FBrf0187382
|Djagaeva et al.
|2005
|-1
REFM|FBrf0180105
|Pielage et al.
|2004
|-1
REFM|FBrf0190110
|Dobens et al.
|2005
|-1
REFM|FBrf0189359
|Szafranski and Goode
|2006
|-1
REFM|FBrf0111489
|Spradling et al.
|1999
|-1
REFM|FBrf0189015
|Tsujimura et al.
|2006
|-1
REFM|FBrf0188210
|Forstemann et al.
|2005
|-1
REFM|FBrf0167484
|Pielage et al.
|2003
|-1
REFM|FBrf0152121
|Roper et al.
|2002
|-1
REFM|FBrf0161562
|Yamashita et al.
|2003
|-1
}

REFDSR
{
RDID|FBrf0132100
|Goldstein and Gunawardena
|2000
ENZ|cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity
CEL|spectrin ; GO:0008091 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0148886
|FlyBase Genome Annotators
|2002-2003
FNC|cytoskeleton organization and biogenesis ; GO:0007010 | inferred from sequence or structural similarity with UniProt:P08032
ENZ|actin binding ; GO:0003779 | inferred from sequence or structural similarity with UniProt:P08032
|calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with UniProt:P08032
CEL|cytoskeleton ; GO:0005856 | inferred from sequence or structural similarity with UniProt:P08032
}

REFDSR
{
RDID|FBrf0152121
|Roper et al.
|2002
ENZ|actin binding ; GO:0003779 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0187325
|Pielage et al.
|2005
FNC|long-term strengthening of neuromuscular junction ; GO:0042062 | inferred from mutant phenotype
|negative regulation of microtubule depolymerization ; GO:0007026 | inferred from mutant phenotype
|regulation of synapse structure ; GO:0050807 | inferred from mutant phenotype
WT|@&agr;-Spec@ functions, with @&bgr;-Spec@, at the presynapse as an
|essential presynaptic scaffold that may link synaptic cell adhesion
|with the stabilization of the underlying microtubule cytoskeleton.
}

REFDSR
{
RDID|FBrf0187387
|Kai et al.
|2005
SYN|&agr;-spec
}

REFDSR
{
RDID|FBrf0187466
|Jin et al.
|2005
SYN|spectrin
}

REFDSR
{
RDID|FBrf0189359
|Szafranski and Goode
|2006
SYN|alfa-Spec
|l(2)gl
}

ALESR
{
ASYM|&agr;-Spec<up>04276</up>
ID|PFal0138601
REF|FBrf0067338
|FBrf0148886
|FBrf0111489
REFDSR
{
RDID|FBrf0067338
|BDGP Project Members
|1994-1999
TRN|FBti0009886 == P{PZ}dlt<up>04276</up>
}

REFDSR
{
RDID|FBrf0111489
|Spradling et al.
|1999
TRN|FBti0009886 == P{PZ}dlt<up>04276</up>
}

REFDSR
{
RDID|FBrf0148886
|FlyBase Genome Annotators
|2002-2003
TRN|FBti0009886 == P{PZ}dlt<up>04276</up>
}

}

ALESR
{
ASYM|&agr;-Spec<up>P4</up>
ID|PFal0188384
REF|FBrf0167484
REFDSR
{
RDID|FBrf0167484
|Pielage et al.
|2003
PRG|FBti0008000 == P{EP}CG13933<up>EP3081</up>
}

}

ALESR
{
ASYM|&agr;-Spec<up>RpS27A.T:Hsap\MYC</up>
ID|PFal0059669
REF|FBrf0092605
REFDSR
{
RDID|FBrf0092605
|Lee et al.
|1997
MD|Construct: The coding region for @&agr;-Spec@ is expressed from the @RpS27A@
|promoter and tagged with @T:Hsap\MYC@. Included within the XbaI-NotI fragment
|of "pWUM-3" (FBrf0079984).
}

}

ALESR
{
ASYM|&agr;-Spec<up>dsRNA.Scer\UAS</up>
ID|PFal0900000
REF|FBrf0187325
REFDSR
{
RDID|FBrf0187325
|Pielage et al.
|2005
MU|in vitro construct | RNAi
|in vitro construct | regulatory fusion
CNS|P{UAS-&agr;-Spec.dsRNA}
PHC|lethal | first instar larval stage with @Scer\GAL4<up>da.G32</up>@
|lethal | third instar larval stage with @Scer\GAL4<up>elav-C155</up>@
|neuroanatomy defective with @Scer\GAL4<up>elav-C155</up>@
|neurophysiology defective with @Scer\GAL4<up>elav-C155</up>@
PHM|bouton with @Scer\GAL4<up>elav-C155</up>@
|microtubule cytoskeleton  with @Scer\GAL4<up>elav-C155</up>@
|axon with @Scer\GAL4<up>elav-C155</up>@
|microtubule cytoskeleton  with @Scer\GAL4<up>elav-C155</up>@
|nerve terminal with @Scer\GAL4<up>elav-C155</up>@
|postsynaptic membrane with @Scer\GAL4<up>elav-C155</up>@
|synapse with @Scer\GAL4<up>elav-C155</up>@
|synaptic vesicle with @Scer\GAL4<up>elav-C155</up>@
PHI|Although expression of @&agr;-Spec<up>dsRNA.Scer\UAS</up>@, under the control
|of @Scer\GAL4<up>elav-C155</up>@, causes late larval lethality, a small proportion
|of escapers survive to early adult stages.
|Expression of @&agr;-Spec<up>dsRNA.Scer\UAS</up>@ in the presynapse, driven
|by @Scer\GAL4<up>elav-C155</up>@, causes an increase in the number and extent
|of synaptic retraction events compared to wild-type synapses. The severity
|of synapse retraction correlates with a decrease in frequency, but
|not amplitude, of spontaneous miniature release events and a decreased
|quantal content, but no change in quantal size. Bouton morphology
|is affected; boutons show a similar active zone organization to wild
|type, but presynaptic vesicle density is severely decreased and vacuoles
|are sometimes present. The postsynaptic SSR is disrupted, although
|the extent of this varies from bouton to bouton; in severe cases, the
|SSR is disorganized and becomes invaded by muscle tissue.
|The microtubule network is disorganized in the nerve terminals of @Scer\GAL4<up>elav-C155</up>@>@&agr;-Spec<up>dsRNA.Scer\UAS</up>@
|mutants. Microtubules are thicker than wild type and do not extend
|to the distal end of the synaptic bouton chain. Axons of the peripheral
|nervous system show large accumulations of vesicles, although there
|is only a minor axonal microtubule disorganization.
|Postsynaptic @&agr;-Spec<up>dsRNA.Scer\UAS</up>@ expression, driven by @Scer\GAL4<up>C57</up>@,
|causes defects in the integrity of the subsynaptic membrane folds but
|does not cause increased synapse retraction.
|Mode of assay: In transgenic Drosophila (intraspecific)
MD|Construct: Expression of an 587 bp inverted repeat of the @&agr;-Spec@ cDNA, separated
|by a @w@ intron, is driven by @Scer\UAS@ sequences. The @&agr;-Spec@
|sequence corresponds to position 430 onwards of the cDNA.
OTH|Transfected into flies to study the the phenotypic consequences of
|dsRNA interference (RNAi) of the @&agr;-Spec@ gene.
}

}

ALESR
{
ASYM|&agr;-Spec<up>rg41</up>
ID|PFal0059667
REF|FBrf0091300
REFDSR
{
RDID|FBrf0091300
|de Cuevas et al.
|1996
AMSO|Lethality can be rescued by @P{>Up-&agr;-spec>}@.
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0082912	CLA 1 engineered fusion gene ; SO:0000288	GSYM 1 &agr;-Spec::Actn	DT 1 30 Oct 06	RESZ 363	REF 1	
GSYM|&agr;-Spec::Actn
ID|PFgn0082912
CLA|engineered_fusion_gene ; SO:0000288
DT|30 Oct 06
REF
{
REFM|FBrf0134715
|Dubreuil and Wang
|2000
|-1
}

REFDSR
{
RDID|FBrf0134715
|Dubreuil and Wang
|2000
WTI|Actn (data from @&agr;-Spec::Actn<up>19.RpS27A</up>@)
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0031491	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;4GT1	DT 1 30 Oct 06	RESZ 2310	FNC 2 glycolipid biosynthesis	CEL 1 Golgi stack	CLOC 1 23C4	ALESR 4	REF 3	
GSYM|&agr;4GT1
ID|PFgn0031491
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|32251
CLOC|23C4
|Limits computationally determined from genome sequence between @P{PZ}lilli<up>00632</up>@ and @P{PZ}toc<up>01361</up>@
FNC|glycolipid biosynthesis ; GO:0009247 | inferred from direct assay
|glycolipid metabolism ; GO:0006664 | non-traceable author statement
CEL|Golgi stack ; GO:0005795 | inferred from electronic annotation
DT|30 Oct 06
REF
{
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0190751
|Mueller et al.
|2005
|-1
REFM|FBrf0132177
|Gene Disruption Project members
|2001-
|-1
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
ENZ|galactosyltransferase activity ; GO:0008378 ; EC:2.4.1.- | inferred from electronic annotation
CEL|Golgi stack ; GO:0005795 | inferred from electronic annotation
}

REFDSR
{
RDID|FBrf0190751
|Mueller et al.
|2005
SYN|CG17223
WTI|H
}

ALESR
{
ASYM|&agr;4GT1<up>EP2097</up>
ID|PFal0131575
REF|FBrf0132177
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0010845 == P{EP}&agr;4GT1<up>EP2097</up>
}

}

ALESR
{
ASYM|&agr;4GT1<up>EP2426</up>
ID|PFal0131574
REF|FBrf0132177
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0011121 == P{EP}&agr;4GT1<up>EP2426</up>
}

}

ALESR
{
ASYM|&agr;4GT1<up>EP797</up>
ID|PFal0900001
REF|FBrf0190751
REFDSR
{
RDID|FBrf0190751
|Mueller et al.
|2005
TRN|FBti0007698 == P{EP}&agr;4GT1<up>EP797</up>
PHI|Expression of @&agr;4GT1<up>EP797</up>@ under the control of @Scer\GAL4<up>GMR.PF</up>@
|has no affect on the eye.
GIC|enhancer of visible phenotype of @H<up>Scer\UAS.cMa</up>@, @Scer\GAL4<up>GMR.PF</up>@
GIA|enhancer of eye phenotype of @H<up>Scer\UAS.cMa</up>@, @Scer\GAL4<up>GMR.PF</up>@
}

}

ALESR
{
ASYM|&agr;4GT1<up>EY00269</up>
ID|PFal0148288
REF|FBrf0132177
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0024088 == P{EPgy2}&agr;4GT1<up>EY00269</up>
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0039378	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;4GT2	DT 1 30 Oct 06	RESZ 919	PDOM 1 INTERPRO:IPR007577 == Glycosyltransferase sugar-binding region containing DXD motif	FNC 2 carbohydrate metabolism	CEL 1 Golgi stack	CLOC 1 96F3	REF 1	
GSYM|&agr;4GT2
ID|PFgn0039378
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|125103
CLOC|96F3
|Limits computationally determined from genome sequence between @P{PZ}l(3)rQ197<up>rQ197</up>@ and @P{lacW}scrib<up>j7B3</up>@
PDOM|IPR007577 == Glycosyltransferase sugar-binding region containing DXD motif
FNC|carbohydrate metabolism ; GO:0005975 | inferred from electronic annotation
|lipid metabolism ; GO:0006629 | inferred from electronic annotation
CEL|Golgi stack ; GO:0005795 | inferred from electronic annotation
DT|30 Oct 06
REF
{
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
ENZ|galactosyltransferase activity ; GO:0008378 ; EC:2.4.1.- | inferred from electronic annotation
CEL|Golgi stack ; GO:0005795 | inferred from electronic annotation
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0025725	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;Cop	DT 1 30 Oct 06	RESZ 2360	PDOM 1 INTERPRO:IPR011990 == Tetratricopeptide-like helical	FNC 1 retrograde vesicle-mediated transport, Golgi to ER	CEL 2 COPI vesicle coat	CLOC 1 62A9	REF 6	
GSYM|&agr;Cop
ID|PFgn0025725
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|79567
CLOC|62A9
|Limits computationally determined from genome sequence between @P{EP}rho<up>EP3704</up>@&@P{PZ}l(3)06226<up>06226</up>@ and @P{PZ}dlt<up>04276</up>@
PDOM|IPR011990 == Tetratricopeptide-like helical
FNC|retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity
ENZ|binding ; GO:0005488 | inferred from electronic annotation
CEL|COPI vesicle coat ; GO:0030126 | inferred from sequence or structural similarity
|COPI vesicle coat ; GO:0030126 | non-traceable author statement
DT|30 Oct 06
REF
{
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0188255
|Cheng et al.
|2005
|-1
REFM|FBrf0191233
|Bjorklund et al.
|2006
|-1
REFM|FBrf0118013
|Merdes
|1998.9.27
|-1
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
REFM|FBrf0190507
|Grieder et al.
|2005
|-1
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
FNC|retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity with SGD_LOCUS:COP1; SGD:S0002304
CEL|COPI vesicle coat ; GO:0030126 | inferred from sequence or structural similarity with SGD_LOCUS:COP1; SGD:S0002304
}

REFDSR
{
RDID|FBrf0118013
|Merdes
|1998.9.27
FNC|retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | non-traceable author statement
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
FNC|intracellular protein transport ; GO:0006886 | inferred from electronic annotation
ENZ|binding ; GO:0005488 | inferred from electronic annotation
|protein transporter activity ; GO:0008565 | inferred from electronic annotation
}

REFDSR
{
RDID|FBrf0188255
|Cheng et al.
|2005
PHP|dsRNA made from templates generated with primers directed against @&agr;Cop@
|that is transfected into S2 treated with Listeria monocytogenes reveals
|@&agr;Cop@ to be involved in Listeria monocytogenes entry and vacuolar
|escape.
}

REFDSR
{
RDID|FBrf0190507
|Grieder et al.
|2005
SYN|&agr;COP
MD|Identified with: LD46584
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0034005	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;PS4	DT 1 30 Oct 06	RESZ 2084	PDOM 4 INTERPRO:IPR013513 == Integrin alpha chain, C-terminal cytoplasmic region	FNC 1 cell adhesion	CEL 2 integrin complex	CLOC 1 51E11	REF 3	
GSYM|&agr;PS4
ID|PFgn0034005
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|64581
CLOC|51E11
|Limits computationally determined from genome sequence between @P{PZ}scb<up>01288</up>@ and @P{lacW}dup<up>k03308</up>@
PDOM|IPR013513 == Integrin alpha chain, C-terminal cytoplasmic region
|IPR013517 == FG-GAP
|IPR013519 == Integrin alpha beta-propellor
|IPR013649 == Integrin alpha-2
FNC|cell adhesion ; GO:0007155 | inferred from sequence or structural similarity
ENZ|cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity
|receptor activity ; GO:0004872 | inferred from sequence or structural similarity
CEL|integrin complex ; GO:0008305 | inferred from sequence or structural similarity
|integrin complex ; GO:0008305 | non-traceable author statement
DT|30 Oct 06
REF
{
REFM|FBrf0129868
|Hynes and Zhao
|2000
|-1
REFM|FBrf0129746
|Brown
|2000
|-1
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
FNC|cell adhesion ; GO:0007155 | inferred from sequence or structural similarity with EMBL:AF041409
ENZ|cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity with EMBL:AF041409
|receptor activity ; GO:0004872 | inferred from sequence or structural similarity with EMBL:AF041409
CEL|integrin complex ; GO:0008305 | inferred from sequence or structural similarity with EMBL:AF041409
}

REFDSR
{
RDID|FBrf0129746
|Brown
|2000
CEL|integrin complex ; GO:0008305 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0129868
|Hynes and Zhao
|2000
ENZ|cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity with FLYBASE:scb; FB:FBgn0003328
|receptor activity ; GO:0004872 | inferred from sequence or structural similarity with FLYBASE:scb; FB:FBgn0003328
CEL|integrin complex ; GO:0008305 | inferred from sequence or structural similarity with FLYBASE:scb; FB:FBgn0003328
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0034880	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;PS5	DT 1 30 Oct 06	RESZ 2040	PDOM 3 INTERPRO:IPR013517 == FG-GAP	FNC 1 cell adhesion	CEL 2 integrin complex	CLOC 1 59E4	REF 3	
GSYM|&agr;PS5
ID|PFgn0034880
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|75998
CLOC|59E4
|Limits computationally determined from genome sequence between @P{PZ}Dcp-1<up>02132</up>@ and @P{EP}apt<up>EP2339</up>@&@P{PZ}apt<up>06369</up>@
PDOM|IPR013517 == FG-GAP
|IPR013519 == Integrin alpha beta-propellor
|IPR013649 == Integrin alpha-2
FNC|cell adhesion ; GO:0007155 | inferred from sequence or structural similarity
ENZ|cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity
|receptor activity ; GO:0004872 | inferred from sequence or structural similarity
CEL|integrin complex ; GO:0008305 | inferred from sequence or structural similarity
|integrin complex ; GO:0008305 | non-traceable author statement
DT|30 Oct 06
REF
{
REFM|FBrf0129868
|Hynes and Zhao
|2000
|-1
REFM|FBrf0129746
|Brown
|2000
|-1
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
FNC|cell adhesion ; GO:0007155 | inferred from sequence or structural similarity with EMBL:AF041409
ENZ|cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity with EMBL:AF041409
|receptor activity ; GO:0004872 | inferred from sequence or structural similarity with EMBL:AF041409
CEL|integrin complex ; GO:0008305 | inferred from sequence or structural similarity with EMBL:AF041409
}

REFDSR
{
RDID|FBrf0129746
|Brown
|2000
CEL|integrin complex ; GO:0008305 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0129868
|Hynes and Zhao
|2000
ENZ|cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity with FLYBASE:scb; FB:FBgn0003328
|receptor activity ; GO:0004872 | inferred from sequence or structural similarity with FLYBASE:scb; FB:FBgn0003328
CEL|integrin complex ; GO:0008305 | inferred from sequence or structural similarity with FLYBASE:scb; FB:FBgn0003328
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0003863	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;Try	DT 1 30 Oct 06	RESZ 586	PDOM 2 INTERPRO:IPR001254 == Peptidase S1 and S6, chymotrypsin/Hap	FNC 1 proteolysis	CEL 1 extracellular region	CLOC 1 47F4	
GSYM|&agr;Try
ID|PFgn0003863
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|59509
CLOC|47F4
|Limits computationally determined from genome sequence between @P{lacW}Fpps<up>k06103</up>@&@P{lacW}Fpps<up>k03514</up>@ and @P{lacW}Tap&dgr;<up>k17005</up>@&@P{lacW}k05103@
PDOM|IPR001254 == Peptidase S1 and S6, chymotrypsin/Hap
|IPR009003 == Peptidase, trypsin-like serine and cysteine
FNC|proteolysis ; GO:0006508 | non-traceable author statement
CEL|extracellular region ; GO:0005576 | non-traceable author statement
DT|30 Oct 06
}
# EOR
GENR
{
RETE|ID 1 PFgn0004236	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;Tub67C	DT 1 30 Oct 06	RESZ 3919	FNC 1 microtubule-based process	CEL 1 microtubule	CLOC 1 67C4	ALESR 1	REF 20	
GSYM|&agr;Tub67C
ID|PFgn0004236
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|87299
CLOC|67C4
|Limits computationally determined from genome sequence between @P{PZ}fry<up>02240</up>@ and @P{lacW}l(3)L0539<up>L0539</up>@&@P{PZ}Dhh1<up>rL562</up>@
FNC|microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0051088
|Erdelyi and Szabad
|1989
|-1
REFM|FBrf0132100
|Goldstein and Gunawardena
|2000
|-1
REFM|FBrf0187222
|Delanoue and Davis
|2005
|-1
REFM|FBrf0189924
|Siegrist and Doe
|2005
|-1
REFM|FBrf0179327
|Martinez-Campos et al.
|2004
|-1
REFM|FBrf0174546
|Pokrywka et al.
|2004
|-1
REFM|FBrf0167770
|Grevengoed et al.
|2003
|-1
REFM|FBrf0129830
|Goldstein and Gunawardena
|2000
|-1
REFM|FBrf0189998
|Bettencourt-Dias et al.
|2005
|-1
REFM|FBrf0191755
|Bettencourt-Dias et al.
|2005
|-1
REFM|FBrf0187387
|Kai et al.
|2005
|-1
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0188261
|Karlin et al.
|2005
|-1
REFM|FBrf0174801
|Izumi et al.
|2004
|-1
REFM|FBrf0141767
|Debec et al.
|2001
|-1
REFM|FBrf0183991
|Mirouse et al.
|2005
|-1
REFM|FBrf0167767
|Rolls et al.
|2003
|-1
REFM|FBrf0190312
|Moussian et al.
|2006
|-1
REFM|FBrf0058107
|Matthews et al.
|1993
|-1
REFM|FBrf0167937
|Ruel et al.
|2003
|-1
}

REFDSR
{
RDID|FBrf0051088
|Erdelyi and Szabad
|1989
GLOC|Maps to the left of th
|Maps to the right of h
}

REFDSR
{
RDID|FBrf0058107
|Matthews et al.
|1993
GLOC|3-32.26 +/- 1.26
|Maps to the left of th
|Maps to the right of h
}

REFDSR
{
RDID|FBrf0129830
|Goldstein and Gunawardena
|2000
FNC|microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0132100
|Goldstein and Gunawardena
|2000
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0167937
|Ruel et al.
|2003
SYN|&agr;-Tub
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
FNC|microtubule-based movement ; GO:0007018 | inferred from electronic annotation
ENZ|GTPase activity ; GO:0003924 | inferred from electronic annotation
}

REFDSR
{
RDID|FBrf0179327
|Martinez-Campos et al.
|2004
SYN|&agr;-tubulin
}

REFDSR
{
RDID|FBrf0187222
|Delanoue and Davis
|2005
SYN|&agr;Tub
}

REFDSR
{
RDID|FBrf0189924
|Siegrist and Doe
|2005
SYN|&agr;tub
}

ALESR
{
ASYM|&agr;Tub67C<up>3</up>
ID|PFal0000010
REF|FBrf0174546
REFDSR
{
RDID|FBrf0174546
|Pokrywka et al.
|2004
GIA2|embryonic/first instar larval cuticle | maternal effect, suppressible | partially by @swa<up>1</up>@/+
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0003884	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;Tub84B	DT 1 30 Oct 06	RESZ 7839	FNC 1 mitotic spindle checkpoint	CEL 1 microtubule	CLOC 1 84B2	ALESR 4	REF 40	
GSYM|&agr;Tub84B
ID|PFgn0003884
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|105557
CLOC|84B2
|Limits computationally determined from genome sequence between @P{lacW}l(3)L2100<up>L2100</up>@ and @P{EP}EP3060<up>EP3060</up>@
FNC|mitotic spindle checkpoint ; GO:0007094 | inferred from direct assay
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0152112
|Rogers et al.
|2002
|-1
REFM|FBrf0093522
|Hutchens et al.
|1997
|-1
REFM|FBrf0066557
|Fuller
|1986
|-1
REFM|FBrf0183991
|Mirouse et al.
|2005
|-1
REFM|FBrf0189751
|Liebl et al.
|2005
|-1
REFM|FBrf0190144
|Mermall et al.
|2005
|-1
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0167937
|Ruel et al.
|2003
|-1
REFM|FBrf0167770
|Grevengoed et al.
|2003
|-1
REFM|FBrf0191763
|Page
|2005
|-1
REFM|FBrf0050548
|Hays et al.
|1989
|-1
REFM|FBrf0161562
|Yamashita et al.
|2003
|-1
REFM|FBrf0190362
|Kleino et al.
|2005
|-1
REFM|FBrf0187491
|Williams and Truman
|2005
|-1
REFM|FBrf0179143
|Braat et al.
|2004
|-1
REFM|FBrf0187332
|Roll-Mecak and Vale
|2005
|-1
REFM|FBrf0167767
|Rolls et al.
|2003
|-1
REFM|FBrf0190711
|Cobbe et al.
|2006
|-1
REFM|FBrf0189998
|Bettencourt-Dias et al.
|2005
|-1
REFM|FBrf0191755
|Bettencourt-Dias et al.
|2005
|-1
REFM|FBrf0141767
|Debec et al.
|2001
|-1
REFM|FBrf0190323
|Steinhauer and Kalderon
|2005
|-1
REFM|FBrf0189896
|Ashraf et al.
|2006
|-1
REFM|FBrf0184251
|Shen and Dahmann
|2005
|-1
REFM|FBrf0187481
|Serbus et al.
|2005
|-1
REFM|FBrf0187387
|Kai et al.
|2005
|-1
REFM|FBrf0191267
|Rosales-Nieves et al.
|2006
|-1
REFM|FBrf0179327
|Martinez-Campos et al.
|2004
|-1
REFM|FBrf0190157
|Sanchez-Soriano et al.
|2005
|-1
REFM|-809837969
|M Mahoney
|2006
|-1
|Curr. Biol. 16: http://www.current-biology.com/cgi/content/full/16/6/564/DC1/
REFM|FBrf0189924
|Siegrist and Doe
|2005
|-1
REFM|FBrf0187222
|Delanoue and Davis
|2005
|-1
REFM|FBrf0174801
|Izumi et al.
|2004
|-1
REFM|-379220059
|Ashraf
|2006
|-1
|Cell 126: 812
REFM|FBrf0187449
|Audibert et al.
|2005
|-1
REFM|FBrf0179258
|Inoue et al.
|2004
|-1
REFM|FBrf0190312
|Moussian et al.
|2006
|-1
REFM|FBrf0132100
|Goldstein and Gunawardena
|2000
|-1
REFM|FBrf0188261
|Karlin et al.
|2005
|-1
REFM|-615930925
|Basto
|2006
|-1
|Cell 125: 1375--1386
}

REFDSR
{
RDID|FBrf0050548
|Hays et al.
|1989
GLOC|3-47.7
|Maps to the left of p
|Maps to the right of Ki
}

REFDSR
{
RDID|FBrf0066557
|Fuller
|1986
GLOC|3-47.7 +/- 0.1
|Maps to the left of p
|Maps to the right of Ki
}

REFDSR
{
RDID|FBrf0132100
|Goldstein and Gunawardena
|2000
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0167937
|Ruel et al.
|2003
SYN|&agr;-Tub
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
FNC|microtubule-based movement ; GO:0007018 | inferred from electronic annotation
ENZ|GTPase activity ; GO:0003924 | inferred from electronic annotation
}

REFDSR
{
RDID|FBrf0179327
|Martinez-Campos et al.
|2004
SYN|&agr;-tubulin
}

REFDSR
{
RDID|FBrf0187449
|Audibert et al.
|2005
SYN|agr;Tub
}

REFDSR
{
RDID|FBrf0190362
|Kleino et al.
|2005
FNC|antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype
MD|RNAi screen using dsRNA made from templates generated with primers
|directed against this gene causes a greater than three-fold increase
|in @AttA@ activity in response to heat-killed E.coli after ecdysone
|treatment in S2 cells.
}

REFDSR
{
RDID|FBrf0187222
|Delanoue and Davis
|2005
SYN|&agr;Tub
}

REFDSR
{
RDID|FBrf0189924
|Siegrist and Doe
|2005
SYN|&agr;tub
}

REFDSR
{
RDID|-809837969
|M Mahoney
|2006
SYN|DM1&agr;
}

ALESR
{
ASYM|&agr;Tub84B<up>Act5C.T:Avic\GFP-S65C,T:Zzzz\His6,T:SV5\V5</up>
ID|PFal0188379
REF|FBrf0179258
|-809837969
|FBrf0152112
|FBrf0187481
REFDSR
{
RDID|FBrf0152112
|Rogers et al.
|2002
MD|Construct: An @Act5C@ promoter drives expression of @&agr;Tub84B@, tagged with
|@T:Avic\GFP<up>S65C</up>@, @T:Zzzz\His6@ and @T:SV5\V5@.
}

REFDSR
{
RDID|FBrf0179258
|Inoue et al.
|2004
PHI|Mode of assay: Drosophila cell culture
}

REFDSR
{
RDID|FBrf0187481
|Serbus et al.
|2005
SYN|GFP::&agr;-tubulin
CNS|FBtp0013497 == P{UASp-GFPS65C-&agr;Tub84B}
}

REFDSR
{
RDID|-809837969
|M Mahoney
|2006
PHI|Mode of assay: Drosophila cell culture
OTH|Carried in a plasmid and transfected into S2 cells.
}

}

ALESR
{
ASYM|&agr;Tub84B<up>Scer\UAS.P\T.T:Avic\GFP-S65C</up>
ID|PFal0119725
REF|-615930925
|FBrf0190157
|FBrf0187491
|FBrf0161562
REFDSR
{
RDID|FBrf0161562
|Yamashita et al.
|2003
CNS|FBtp0013497 == P{UASp-GFPS65C-&agr;Tub84B}
}

REFDSR
{
RDID|FBrf0187491
|Williams and Truman
|2005
CNS|FBtp0013497 == P{UASp-GFPS65C-&agr;Tub84B}
}

REFDSR
{
RDID|FBrf0190157
|Sanchez-Soriano et al.
|2005
CNS|FBtp0013497 == P{UASp-GFPS65C-&agr;Tub84B}
}

REFDSR
{
RDID|-615930925
|Basto
|2006
CNS|P{UASp-GFPS65C-&agr;Tub84B}
}

}

ALESR
{
ASYM|&agr;Tub84B<up>Scer\UAS.T:Hsap\MYC</up>
ID|PFal0148523
REF|FBrf0189751
REFDSR
{
RDID|FBrf0189751
|Liebl et al.
|2005
CNS|FBtp0017457 == P{UAS-&agr;Tub84B.Myc}
PHM|synapse  with @Scer\GAL4<up>how-24B</up>@
|microtubule with @Scer\GAL4<up>how-24B</up>@
PHI|Expression of @&agr;Tub84B<up>Scer\UAS.T:Hsap\MYC</up>@ in postsynaptic muscles,
|driven by @Scer\GAL4<up>how-24B</up>@, results in the doubling of microtubule
|density. There is a concomitant increase in the size and number of
|postsynaptic glutamate receptor clusters.
}

}

ALESR
{
ASYM|&agr;Tub84B<up>unspecified</up>
ID|PFal0089852
REF|FBrf0093522
REFDSR
{
RDID|FBrf0093522
|Hutchens et al.
|1997
PHC|(with &agr;Tub84B<up>2</up>) male semi-sterile
|(with &agr;Tub84B<up>5</up>) male semi-sterile
|(with &agr;Tub84B<up>6</up>) male semi-sterile
|(with &agr;Tub84B<up>7</up>) male semi-sterile
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0003885	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;Tub84D	DT 1 30 Oct 06	RESZ 3714	FNC 1 microtubule-based process	CEL 1 microtubule	CLOC 1 84D9	REF 25	
GSYM|&agr;Tub84D
ID|PFgn0003885
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|106052
CLOC|84D9
|Limits computationally determined from genome sequence between @P{EP}EP3060<up>EP3060</up>@ and @P{PZ}grn<up>05930</up>@
FNC|microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0187392
|Orihara-Ono et al.
|2005
|-1
REFM|FBrf0132100
|Goldstein and Gunawardena
|2000
|-1
REFM|FBrf0187222
|Delanoue and Davis
|2005
|-1
REFM|FBrf0191233
|Bjorklund et al.
|2006
|-1
REFM|FBrf0189751
|Liebl et al.
|2005
|-1
REFM|FBrf0179327
|Martinez-Campos et al.
|2004
|-1
REFM|FBrf0167770
|Grevengoed et al.
|2003
|-1
REFM|FBrf0129830
|Goldstein and Gunawardena
|2000
|-1
REFM|FBrf0189998
|Bettencourt-Dias et al.
|2005
|-1
REFM|FBrf0191755
|Bettencourt-Dias et al.
|2005
|-1
REFM|FBrf0187387
|Kai et al.
|2005
|-1
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0188261
|Karlin et al.
|2005
|-1
REFM|FBrf0184251
|Shen and Dahmann
|2005
|-1
REFM|FBrf0174801
|Izumi et al.
|2004
|-1
REFM|FBrf0187449
|Audibert et al.
|2005
|-1
REFM|FBrf0141767
|Debec et al.
|2001
|-1
REFM|FBrf0183991
|Mirouse et al.
|2005
|-1
REFM|FBrf0167767
|Rolls et al.
|2003
|-1
REFM|FBrf0190312
|Moussian et al.
|2006
|-1
REFM|FBrf0191763
|Page
|2005
|-1
REFM|FBrf0187471
|Major and Irvine
|2005
|-1
REFM|FBrf0167937
|Ruel et al.
|2003
|-1
REFM|FBrf0187332
|Roll-Mecak and Vale
|2005
|-1
REFM|FBrf0179207
|Foley and O'Farrell
|2004
|-1
}

REFDSR
{
RDID|FBrf0129830
|Goldstein and Gunawardena
|2000
FNC|microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0132100
|Goldstein and Gunawardena
|2000
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0167937
|Ruel et al.
|2003
SYN|&agr;-Tub
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
FNC|microtubule-based movement ; GO:0007018 | inferred from electronic annotation
ENZ|GTPase activity ; GO:0003924 | inferred from electronic annotation
}

REFDSR
{
RDID|FBrf0179327
|Martinez-Campos et al.
|2004
SYN|&agr;-tubulin
}

REFDSR
{
RDID|FBrf0187449
|Audibert et al.
|2005
SYN|agr;Tub
}

REFDSR
{
RDID|FBrf0187222
|Delanoue and Davis
|2005
SYN|&agr;Tub
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0003886	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &agr;Tub85E	DT 1 30 Oct 06	RESZ 2822	FNC 2 cellular physiological process	CEL 1 microtubule	CLOC 1 85E6	REF 15	
GSYM|&agr;Tub85E
ID|PFgn0003886
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|108257
CLOC|85E6
|Limits computationally determined from genome sequence between @P{EP}Crc<up>EP3006</up>@ and @P{lacW}s2681@
FNC|cellular physiological process ; GO:0050875 | inferred from mutant phenotype
|mitotic spindle checkpoint ; GO:0007094 | inferred from direct assay
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0190312
|Moussian et al.
|2006
|-1
REFM|FBrf0132100
|Goldstein and Gunawardena
|2000
|-1
REFM|FBrf0188261
|Karlin et al.
|2005
|-1
REFM|FBrf0187449
|Audibert et al.
|2005
|-1
REFM|FBrf0179327
|Martinez-Campos et al.
|2004
|-1
REFM|FBrf0167770
|Grevengoed et al.
|2003
|-1
REFM|FBrf0167767
|Rolls et al.
|2003
|-1
REFM|FBrf0180120
|Inbal et al.
|2004
|-1
REFM|FBrf0190144
|Mermall et al.
|2005
|-1
REFM|FBrf0187471
|Major and Irvine
|2005
|-1
REFM|FBrf0187392
|Orihara-Ono et al.
|2005
|-1
REFM|FBrf0174801
|Izumi et al.
|2004
|-1
REFM|FBrf0137313
|Hoyle et al.
|2001
|-1
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0167937
|Ruel et al.
|2003
|-1
}

REFDSR
{
RDID|FBrf0132100
|Goldstein and Gunawardena
|2000
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0137313
|Hoyle et al.
|2001
WTI|&bgr;Tub85D (data from @&agr;Tub85E<up>&bgr;Tub85D.PH</up>@)
}

REFDSR
{
RDID|FBrf0167937
|Ruel et al.
|2003
SYN|&agr;-Tub
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
FNC|microtubule-based movement ; GO:0007018 | inferred from electronic annotation
ENZ|GTPase activity ; GO:0003924 | inferred from electronic annotation
}

REFDSR
{
RDID|FBrf0179327
|Martinez-Campos et al.
|2004
SYN|&agr;-tubulin
}

REFDSR
{
RDID|FBrf0180120
|Inbal et al.
|2004
SYN|&agr;85E-tub
}

REFDSR
{
RDID|FBrf0187449
|Audibert et al.
|2005
SYN|agr;Tub
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0025724	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &bgr;'Cop	DT 1 30 Oct 06	RESZ 2016	FNC 3 ER to Golgi vesicle-mediated transport	CEL 1 COPI vesicle coat	CLOC 1 34B9	REF 6	
GSYM|&bgr;'Cop
ID|PFgn0025724
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|43135
CLOC|34B9
|Limits computationally determined from genome sequence between @P{lacW}l(2)k00302<up>k00302</up>@ and @P{PZ}kuz<up>03782</up>@&@P{lacW}kuz<up>k14817</up>@
FNC|ER to Golgi vesicle-mediated transport ; GO:0006888 | non-traceable author statement
|Golgi vesicle budding ; GO:0048194 | non-traceable author statement
|retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | non-traceable author statement
CEL|COPI vesicle coat ; GO:0030126 | non-traceable author statement
DT|30 Oct 06
REF
{
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0191233
|Bjorklund et al.
|2006
|-1
REFM|FBrf0131779
|Swiss-Prot Project Members
|2000.10.1
|-1
REFM|FBrf0118012
|Merdes
|1998.6.2
|-1
REFM|FBrf0118011
|Merdes
|1998.6.2
|-1
REFM|FBrf0190507
|Grieder et al.
|2005
|-1
}

REFDSR
{
RDID|FBrf0118011
|Merdes
|1998.6.2
FNC|ER to Golgi vesicle-mediated transport ; GO:0006888 | non-traceable author statement
|retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | non-traceable author statement
}

REFDSR
{
RDID|FBrf0118012
|Merdes
|1998.6.2
FNC|retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | non-traceable author statement
}

REFDSR
{
RDID|FBrf0131779
|Swiss-Prot Project Members
|2000.10.1
FNC|retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | non-traceable author statement
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
FNC|intracellular protein transport ; GO:0006886 | inferred from electronic annotation
ENZ|protein transporter activity ; GO:0008565 | inferred from electronic annotation
}

REFDSR
{
RDID|FBrf0190507
|Grieder et al.
|2005
SYN|&bgr;'COP
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0003471	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &bgr;-Spec	DT 1 30 Oct 06	RESZ 6883	PDOM 1 INTERPRO:IPR011993 == Pleckstrin homology-type	FNC 4 long-term strengthening of neuromuscular junction	CEL 1 spectrin	CLOC 1 16B10--12	ALESR 4	REF 11	
GSYM|&bgr;-Spec
ID|PFgn0003471
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|21380-16737
CLOC|16B10--12
|Limits computationally determined from genome sequence between @P{EP}baz<up>EP1446</up>@ and @P{EP}EP1464@
PDOM|IPR011993 == Pleckstrin homology-type
FNC|long-term strengthening of neuromuscular junction ; GO:0042062 | inferred from mutant phenotype
|negative regulation of microtubule depolymerization ; GO:0007026 | inferred from mutant phenotype
|neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype
|regulation of synapse structure ; GO:0050807 | inferred from mutant phenotype
ENZ|actin binding ; GO:0003779 | inferred from sequence or structural similarity
|actin filament binding ; GO:0051015 | inferred from sequence or structural similarity
|calmodulin binding ; GO:0005516 | inferred from sequence or structural similarity
|cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity
CEL|spectrin ; GO:0008091 | inferred from sequence or structural similarity
DT|30 Oct 06
REV|FBrf0132360
REF
{
REFM|FBrf0107552
|Schaefer et al.
|1999.3.29
|-1
REFM|FBrf0132100
|Goldstein and Gunawardena
|2000
|-1
REFM|FBrf0152121
|Roper et al.
|2002
|-1
REFM|FBrf0188261
|Karlin et al.
|2005
|-1
REFM|FBrf0132177
|Gene Disruption Project members
|2001-
|-1
REFM|FBrf0167766
|Roper and Brown
|2003
|-1
REFM|FBrf0126673
|Hynes
|1999.11
|-1
REFM|FBrf0187387
|Kai et al.
|2005
|-1
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
REFM|FBrf0187325
|Pielage et al.
|2005
|-1
REFM|FBrf0104946
|FlyBase
|1996-
|-1
}

REFDSR
{
RDID|FBrf0104946
|FlyBase
|1996-
AM|Source for merge of: &bgr;-Spec anon-EST:fe1B3
|Source for merge of &bgr;-Spec anon-EST:fe1B3 was sequence comparison
|(date:030620).
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
ENZ|actin filament binding ; GO:0051015 | inferred from sequence or structural similarity with UniProt:Q01082
|calmodulin binding ; GO:0005516 | inferred from sequence or structural similarity with UniProt:Q01082
CEL|spectrin ; GO:0008091 | inferred from sequence or structural similarity with UniProt:Q01082
}

REFDSR
{
RDID|FBrf0107552
|Schaefer et al.
|1999.3.29
SYN|l(1)G0074
|l(1)G0108
}

REFDSR
{
RDID|FBrf0126673
|Hynes
|1999.11
ENZ|actin binding ; GO:0003779 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0132100
|Goldstein and Gunawardena
|2000
ENZ|cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity
CEL|spectrin ; GO:0008091 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0152121
|Roper et al.
|2002
ENZ|actin binding ; GO:0003779 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0187325
|Pielage et al.
|2005
FNC|long-term strengthening of neuromuscular junction ; GO:0042062 | inferred from mutant phenotype
|negative regulation of microtubule depolymerization ; GO:0007026 | inferred from mutant phenotype
|regulation of synapse structure ; GO:0050807 | inferred from mutant phenotype
WT|@&bgr;-Spec@ functions, with @&agr;-Spec@, at the presynapse as an
|essential presynaptic scaffold that may link synaptic cell adhesion
|with the stabilization of the underlying microtubule cytoskeleton.
}

REFDSR
{
RDID|FBrf0187387
|Kai et al.
|2005
SYN|&bgr;-spec
}

ALESR
{
ASYM|&bgr;-Spec<up>G0074</up>
ID|PFal0096832
REF|FBrf0107552
REFDSR
{
RDID|FBrf0107552
|Schaefer et al.
|1999.3.29
SYN|l(1)G0074<up>G0074</up>
}

}

ALESR
{
ASYM|&bgr;-Spec<up>G0108</up>
ID|PFal0096822
REF|FBrf0107552
REFDSR
{
RDID|FBrf0107552
|Schaefer et al.
|1999.3.29
SYN|l(1)G0108<up>G0108</up>
}

}

ALESR
{
ASYM|&bgr;-Spec<up>KG02312</up>
ID|PFal0131827
REF|FBrf0132177
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0021349 == P{SUPor-P}&bgr;-Spec<up>KG02312</up>
}

}

ALESR
{
ASYM|&bgr;-Spec<up>dsRNA.Scer\UAS</up>
ID|PFal0900002
REF|FBrf0187325
REFDSR
{
RDID|FBrf0187325
|Pielage et al.
|2005
MU|in vitro construct | RNAi
|in vitro construct | regulatory fusion
CNS|P{UAS-&agr;-Spec.dsRNA}
PHC|lethal | first instar larval stage with @Scer\GAL4<up>da.G32</up>@
|lethal | third instar larval stage with @Scer\GAL4<up>sca-537.4</up>@
|neuroanatomy defective with @Scer\GAL4<up>sca-537.4</up>@
|neurophysiology defective with @Scer\GAL4<up>sca-537.4</up>@
PHM|bouton with @Scer\GAL4<up>sca-537.4</up>@
|microtubule cytoskeleton  with @Scer\GAL4<up>sca-537.4</up>@
|axon with @Scer\GAL4<up>sca-537.4</up>@
|postsynaptic membrane with @Scer\GAL4<up>sca-537.4</up>@
|synapse with @Scer\GAL4<up>sca-537.4</up>@
|synaptic vesicle with @Scer\GAL4<up>sca-537.4</up>@
PHI|Although expression of @&bgr;-Spec<up>dsRNA.Scer\UAS</up>@, under the control
|of @Scer\GAL4<up>sca-537.4</up>@, causes late larval lethality, a small proportion
|of escapers survive to early adult stages.
|Expression of @&bgr;-Spec<up>dsRNA.Scer\UAS</up>@ in the presynapse, driven
|by @Scer\GAL4<up>sca-537.4</up>@, causes an increase in the number and extent
|of synaptic retraction events compared to wild-type synapses. The severity
|of synapse retraction correlates with a decrease in frequency, but
|not amplitude, of spontaneous miniature release events and a decreased
|quantal content, but no change in quantal size. Bouton morphology
|is perturbed. There are large accumulations of vesicles in the axons,
|although changes in axonal microtubule organization are minor.
|Postsynaptic @&bgr;-Spec<up>dsRNA.Scer\UAS</up>@ expression, driven by @Scer\GAL4<up>C57</up>@,
|causes defects in the integrity of the subsynaptic membrane folds but
|does not cause increased synapse retraction.
|Mode of assay: In transgenic Drosophila (intraspecific)
MD|Construct: Expression of an 544 bp inverted repeat of the @&bgr;-Spec@ cDNA, separated
|by a @w@ intron, is driven by @Scer\UAS@ sequences. The @&bgr;-Spec@
|sequence corresponds to position 1687 onwards of the cDNA.
OTH|Transfected into flies to study the the phenotypic consequences of
|dsRNA interference (RNAi) of the @&bgr;-Spec@ gene.
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0063368	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &bgr;-glycoprotein-hormone-related	DT 1 30 Oct 06	RESZ 459	REF 1	
GSYM|&bgr;-glycoprotein-hormone-related
ID|PFgn0063368
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
DT|30 Oct 06
REF
{
REFM|FBrf0104946
|FlyBase
|1996-
|-1
}

REFDSR
{
RDID|FBrf0104946
|FlyBase
|1996-
AM|Source for merge of: &bgr;-glycoprotein-hormone-related CG40041
|Source for merge of &bgr;-glycoprotein-hormone-related CG40041 was
|sequence comparison (date:031111).
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0027538	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &bgr;4GalNAcTA	DT 1 30 Oct 06	RESZ 1555	FNC 1 N-acetylglucosamine metabolism	CLOC 1 50E6	ALESR 1	REF 4	
GSYM|&bgr;4GalNAcTA
ID|PFgn0027538
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|63300
CLOC|50E6
|Limits computationally determined from genome sequence between @P{lacW}l(2)s3475<up>s3475</up>@&@P{lacW}Hsc70-5<up>k04907</up>@ and @P{PZ}Tfb1<up>06949</up>@&@P{PZ}l(2)03563<up>03563</up>@
FNC|N-acetylglucosamine metabolism ; GO:0006044 | inferred from direct assay
DT|30 Oct 06
REF
{
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0104946
|FlyBase
|1996-
|-1
REFM|FBrf0149811
|Davies
|2001.3.15
|-1
REFM|FBrf0182892
|Haines and Irvine
|2005
|-1
}

REFDSR
{
RDID|FBrf0104946
|FlyBase
|1996-
AM|Source for merge of: &bgr;4GalNAcTA anon-WO0118547.128
|Source for merge of &bgr;4GalNAcTA anon-WO0118547.128 was sequence
|comparison (date:051113).
}

REFDSR
{
RDID|FBrf0149811
|Davies
|2001.3.15
OTH|Area matching Drosophila EST AA202366.
|Probable intron in gene represented by EST AA202366.
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
ENZ|xylose isomerase activity ; GO:0009045 ; EC:5.3.1.5 | inferred from electronic annotation
}

ALESR
{
ASYM|&bgr;4GalNAcTA<up>MtnA.T:SV5\V5,T:Zzzz\His6</up>
ID|PFal0176439
REF|FBrf0182892
REFDSR
{
RDID|FBrf0182892
|Haines and Irvine
|2005
OTH|Carried in plasmid "pMTWB-&bgr;4GalNAcTA:V5:His", transfected into
|S2 cells and used to characterize the enzymatic activity of the protein
|produced.
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0039625	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &bgr;4GalNAcTB	DT 1 30 Oct 06	RESZ 1803	FNC 1 N-acetylglucosamine metabolism	CLOC 1 98F5	ALESR 4	
GSYM|&bgr;4GalNAcTB
ID|PFgn0039625
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|127893
CLOC|98F5
|Limits computationally determined from genome sequence between @P{PZ}l(3)06487<up>06487</up>@ and @P{EP}EP3390<up>EP3390</up>@
FNC|N-acetylglucosamine metabolism ; GO:0006044 | inferred from direct assay
DT|30 Oct 06
ALESR
{
ASYM|&bgr;4GalNAcTB<up>BIP.MtnA.T:SV5\V5,T:Zzzz\His6</up>
ID|PFal0176438
REF|FBrf0182892
REFDSR
{
RDID|FBrf0182892
|Haines and Irvine
|2005
OTH|Carried in plasmid "pMTIB-&bgr;4GalNAcTB:V5:His", transfected into
|S2 cells and used to characterize the enzymatic activity of the protein
|produced.
}

}

ALESR
{
ASYM|&bgr;4GalNAcTB<up>BIP.MtnA</up>
ID|PFal0176437
REF|FBrf0182892
REFDSR
{
RDID|FBrf0182892
|Haines and Irvine
|2005
OTH|Carried in plasmid "pMTIB-Tm&bgr;4GalNAcTB", transfected into S2 cells
|and used to characterize the enzymatic activity of the protein produced.
}

}

ALESR
{
ASYM|&bgr;4GalNAcTB<up>MtnA.PH</up>
ID|PFal0176434
REF|FBrf0182892
REFDSR
{
RDID|FBrf0182892
|Haines and Irvine
|2005
OTH|Carried in plasmid "pMTWB-&bgr;4GalNAcTB", transfected into S2 cells
|and used to characterize the enzymatic activity of the protein produced.
}

}

ALESR
{
ASYM|&bgr;4GalNAcTB<up>MtnA.T:SV5\V5,T:Zzzz\His6</up>
ID|PFal0176433
REF|FBrf0182892
REFDSR
{
RDID|FBrf0182892
|Haines and Irvine
|2005
OTH|Carried in plasmid "pMTWB-&bgr;4GalNAcTB:V5:His", transfected into
|S2 cells and used to characterize the enzymatic activity of the protein
|produced.
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0039258	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &bgr;4GalT7	DT 1 30 Oct 06	RESZ 2667	FNC 1 proteoglycan biosynthesis	CEL 2 Golgi apparatus	CLOC 1 96B16	ALESR 2	REF 4	
GSYM|&bgr;4GalT7
ID|PFgn0039258
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|124311
CLOC|96B16
|Limits computationally determined from genome sequence between @P{PZ}ssh<up>01207</up>@ and @P{lacW}OstStt3<up>j2D9</up>@
FNC|proteoglycan biosynthesis ; GO:0030166 | inferred from sequence or structural similarity
ENZ|metal ion binding ; GO:0046872 | inferred from sequence or structural similarity
|xylosylprotein 4-beta-galactosyltransferase activity ; GO:0046525 ; EC:2.4.1.133 | inferred from sequence or structural similarity
CEL|Golgi apparatus ; GO:0005794 | inferred from direct assay
|integral to membrane ; GO:0016021 | inferred from sequence or structural similarity
DT|30 Oct 06
REV|FBrf0155642
REF
{
REFM|FBrf0104946
|FlyBase
|1996-
|-1
REFM|FBrf0184340
|Gene Disruption Project members and Exelixis
|2005
|-1
REFM|FBrf0151720
|Vadaie et al.
|2002
|-1
REFM|FBrf0159024
|Takemae et al.
|2003
|-1
}

REFDSR
{
RDID|FBrf0104946
|FlyBase
|1996-
AM|Source for identity of: &bgr;4GalT7 CG11780
|Source for identity of &bgr;4GalT7 CG11780 was sequence comparison
|(date:021108).
}

REFDSR
{
RDID|FBrf0151720
|Vadaie et al.
|2002
FNC|proteoglycan biosynthesis ; GO:0030166 | inferred from sequence or structural similarity with HUGO:B4GALT7; OMIM:604327
ENZ|xylosylprotein 4-beta-galactosyltransferase activity ; GO:0046525 ; EC:2.4.1.133 | inferred from sequence or structural similarity with HUGO:B4GALT7; OMIM:604327
|xylosylprotein 4-beta-galactosyltransferase activity ; GO:0046525 ; EC:2.4.1.133 | inferred from sequence or structural similarity with WB:sqv-3; WP:CE00306
}

REFDSR
{
RDID|FBrf0159024
|Takemae et al.
|2003
FNC|proteoglycan biosynthesis ; GO:0030166 | inferred from sequence or structural similarity with HUGO:B4GALT1; OMIM:137060
ENZ|metal ion binding ; GO:0046872 | inferred from sequence or structural similarity with HUGO:B4GALT1; OMIM:137060
CEL|integral to membrane ; GO:0016021 | inferred from sequence or structural similarity
}

ALESR
{
ASYM|&bgr;4GalT7<up>Act5C.T:Avic\GFP</up>
ID|PFal0138598
REF|FBrf0151720
REFDSR
{
RDID|FBrf0151720
|Vadaie et al.
|2002
OTH|Carried in plasmid "pAc5.1DmGalT-VII-GFP" and transfected into S2 cells
|to study the subcellular localization of the protein produced.
}

}

ALESR
{
ASYM|&bgr;4GalT7<up>c00101</up>
ID|PFal0188373
REF|FBrf0184340
REFDSR
{
RDID|FBrf0184340
|Gene Disruption Project members and Exelixis
|2005
AMIS|Separable from: @PBac{PB}CG9171<up>c00101</up>@.
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0008635	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &bgr;Cop	DT 1 30 Oct 06	RESZ 2994	PDOM 1 INTERPRO:IPR009028 == AP2 clathrin adaptor, alpha and beta chain, appendage	FNC 2 retrograde vesicle-mediated transport, Golgi to ER	CEL 2 COPI vesicle coat	CLOC 1 17A9	REF 9	
GSYM|&bgr;Cop
ID|PFgn0008635
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|22466
CLOC|17A9
|Limits computationally determined from genome sequence between @P{EP}EP1378@ and @P{EP}CG32549<up>EP1317</up>@
PDOM|IPR009028 == AP2 clathrin adaptor, alpha and beta chain, appendage
FNC|retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity
|retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | non-traceable author statement
ENZ|binding ; GO:0005488 | inferred from electronic annotation
CEL|COPI vesicle coat ; GO:0030126 | inferred from sequence or structural similarity
|Golgi apparatus ; GO:0005794 | inferred from direct assay
DT|30 Oct 06
REF
{
REFM|FBrf0124031
|Swiss-Prot Project Members
|1995.6.1
|-1
REFM|FBrf0188255
|Cheng et al.
|2005
|-1
REFM|-1032776461
|Hollien
|2006
|-1
|Science 313: http://www.sciencemag.org/cgi/content/full/313/5783/104/DC1
REFM|FBrf0190507
|Grieder et al.
|2005
|-1
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
REFM|FBrf0191233
|Bjorklund et al.
|2006
|-1
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0191232
|Bard et al.
|2006
|-1
REFM|FBrf0104946
|FlyBase
|1996-
|-1
}

REFDSR
{
RDID|FBrf0104946
|FlyBase
|1996-
AM|Source for merge of: &bgr;Cop BcDNA:GH09317
|Source for merge of &bgr;Cop BcDNA:GH09317 was sequence comparison
|(date:990717).
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
FNC|retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity with SGD_LOCUS:SEC26; SGD:S0002646
CEL|COPI vesicle coat ; GO:0030126 | inferred from sequence or structural similarity with SGD_LOCUS:SEC26; SGD:S0002646
}

REFDSR
{
RDID|FBrf0124031
|Swiss-Prot Project Members
|1995.6.1
FNC|retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | non-traceable author statement
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
FNC|protein targeting ; GO:0006605 | inferred from electronic annotation
ENZ|binding ; GO:0005488 | inferred from electronic annotation
CEL|Golgi stack ; GO:0005795 | inferred from electronic annotation
}

REFDSR
{
RDID|FBrf0188255
|Cheng et al.
|2005
PHP|dsRNA made from templates generated with primers directed against @&bgr;Cop@
|that is transfected into S2 treated with Listeria monocytogenes reveals
|@&bgr;Cop@ to be involved in Listeria monocytogenes entry and vacuolar
|escape.
}

REFDSR
{
RDID|FBrf0190507
|Grieder et al.
|2005
SYN|&bgr;COP
MD|Identified with: GH09317
}

REFDSR
{
RDID|FBrf0191232
|Bard et al.
|2006
SYN|&bgr;-COP
}

REFDSR
{
RDID|-1032776461
|Hollien
|2006
SYN|CG6223
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0010395	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &bgr;Int-&ngr;	DT 1 30 Oct 06	RESZ 2806	PDOM 4 INTERPRO:IPR002369 == Integrin, beta chain N-terminal	FNC 2 cell-matrix adhesion	CEL 2 integrin complex	CLOC 1 39A1	ALESR 2	REF 8	
GSYM|&bgr;Int-&ngr;
ID|PFgn0010395
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|48413
CLOC|39A1
|Limits computationally determined from genome sequence between @P{PZ}l(2)38EFd<up>04530</up>@ and @P{PZ}l(2)05287<up>05287</up>@
PDOM|IPR002369 == Integrin, beta chain N-terminal
|IPR012012 == Integrin, beta subunit
|IPR013032 == EGF-like region
|IPR013111 == EGF, extracellular
FNC|cell-matrix adhesion ; GO:0007160 | traceable author statement
|heterophilic cell adhesion ; GO:0007157 | traceable author statement
CEL|integrin complex ; GO:0008305 | inferred from sequence or structural similarity
|integrin complex ; GO:0008305 | traceable author statement
DT|30 Oct 06
REF
{
REFM|FBrf0149813
|Davies
|2001.3.15
|-1
REFM|FBrf0135708
|Kraut et al.
|2001
|-1
REFM|FBrf0183998
|Hekmat-Scafe et al.
|2005
|-1
REFM|FBrf0180169
|Devenport and Brown
|2004
|-1
REFM|FBrf0129746
|Brown
|2000
|-1
REFM|FBrf0135968
|Kraut et al.
|2001
|-1
REFM|FBrf0132177
|Gene Disruption Project members
|2001-
|-1
REFM|FBrf0058122
|Yee and Hynes
|1993
|-1
}

REFDSR
{
RDID|FBrf0058122
|Yee and Hynes
|1993
CEL|integrin complex ; GO:0008305 | inferred from sequence or structural similarity with FLYBASE:mys; FB:FBgn0004657
}

REFDSR
{
RDID|FBrf0129746
|Brown
|2000
CEL|integrin complex ; GO:0008305 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0149813
|Davies
|2001.3.15
OTH|Area matching Drosophila Integrin beta subunit gene, Acc. No. L13305.
|Probable Intron in Drosophila integrin gene.
}

ALESR
{
ASYM|&bgr;Int-&ngr;<up>BG01037</up>
ID|PFal0126659
REF|FBrf0132177
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0018406 == P{GT1}&bgr;Int-&ngr;<up>BG01037</up>
}

}

ALESR
{
ASYM|&bgr;Int-&ngr;<up>EP2235</up>
ID|PFal0123349
REF|FBrf0180169
|FBrf0132177
|FBrf0183998
|FBrf0135708
|FBrf0135968
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0010963 == P{EP}&bgr;Int-&ngr;<up>EP2235</up>
}

REFDSR
{
RDID|FBrf0135708
|Kraut et al.
|2001
TRN|FBti0010963 == P{EP}&bgr;Int-&ngr;<up>EP2235</up>
}

REFDSR
{
RDID|FBrf0135968
|Kraut et al.
|2001
TRN|FBti0010963 == P{EP}&bgr;Int-&ngr;<up>EP2235</up>
}

REFDSR
{
RDID|FBrf0180169
|Devenport and Brown
|2004
TRN|FBti0010963 == P{EP}&bgr;Int-&ngr;<up>EP2235</up>
}

REFDSR
{
RDID|FBrf0183998
|Hekmat-Scafe et al.
|2005
TRN|FBti0010963 == P{EP}&bgr;Int-&ngr;<up>EP2235</up>
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0010357	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &bgr;Try	DT 1 30 Oct 06	RESZ 597	PDOM 1 INTERPRO:IPR001254 == Peptidase S1 and S6, chymotrypsin/Hap	FNC 1 proteolysis	CEL 1 extracellular region	CLOC 1 47F4	REF 1	
GSYM|&bgr;Try
ID|PFgn0010357
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|59509
CLOC|47F4
|Limits computationally determined from genome sequence between @P{lacW}Fpps<up>k06103</up>@&@P{lacW}Fpps<up>k03514</up>@ and @P{lacW}Tap&dgr;<up>k17005</up>@&@P{lacW}k05103@
PDOM|IPR001254 == Peptidase S1 and S6, chymotrypsin/Hap
FNC|proteolysis ; GO:0006508 | non-traceable author statement
CEL|extracellular region ; GO:0005576 | non-traceable author statement
DT|30 Oct 06
REF
{
REFM|FBrf0191233
|Bjorklund et al.
|2006
|-1
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0003887	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &bgr;Tub56D	DT 1 30 Oct 06	RESZ 3952	PDOM 1 INTERPRO:IPR000158 == Cell division protein FtsZ	FNC 2 microtubule-based process	CEL 2 microtubule	CLOC 1 56D7--8	ALESR 1	REF 19	
GSYM|&bgr;Tub56D
ID|PFgn0003887
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|71027-10974
CLOC|56D7--8
|Limits computationally determined from genome sequence between @P{lacW}hts<up>k06121</up>@ and @P{lacW}l(2)k00705<up>k00705</up>@&@P{lacW}mei-W68<up>k05603</up>@
PDOM|IPR000158 == Cell division protein FtsZ
FNC|microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity
|muscle attachment ; GO:0016203 | traceable author statement
ENZ|GTP binding ; GO:0005525 | inferred from sequence or structural similarity
|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
|tubulin ; GO:0045298 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0190293
|Hanson et al.
|2005
|-1
REFM|FBrf0190713
|Coulson et al.
|2005
|-1
REFM|FBrf0132100
|Goldstein and Gunawardena
|2000
|-1
REFM|FBrf0191233
|Bjorklund et al.
|2006
|-1
REFM|FBrf0179435
|Schnorrer and Dickson
|2004
|-1
REFM|FBrf0137313
|Hoyle et al.
|2001
|-1
REFM|FBrf0189751
|Liebl et al.
|2005
|-1
REFM|FBrf0191744
|Baena-Lopez
|2005
|-1
REFM|FBrf0132177
|Gene Disruption Project members
|2001-
|-1
REFM|FBrf0167770
|Grevengoed et al.
|2003
|-1
REFM|FBrf0187296
|Baena-Lopez et al.
|2005
|-1
REFM|FBrf0187466
|Jin et al.
|2005
|-1
REFM|FBrf0180120
|Inbal et al.
|2004
|-1
REFM|FBrf0045820
|Michiels et al.
|1987
|-1
REFM|FBrf0183733
|Mace and Tugores
|2004
|-1
REFM|FBrf0189268
|Xu et al.
|2006
|-1
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0188261
|Karlin et al.
|2005
|-1
REFM|FBrf0127125
|Hoyle et al.
|2000
|-1
}

REFDSR
{
RDID|FBrf0045820
|Michiels et al.
|1987
FNC|microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity with UniProt:P05218
ENZ|GTP binding ; GO:0005525 | inferred from sequence or structural similarity with UniProt:P05218
CEL|tubulin ; GO:0045298 | inferred from sequence or structural similarity with UniProt:P05218
}

REFDSR
{
RDID|FBrf0127125
|Hoyle et al.
|2000
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0132100
|Goldstein and Gunawardena
|2000
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0137313
|Hoyle et al.
|2001
WTI|&bgr;Tub85D (data from @&bgr;Tub56D<up>&bgr;Tub85D.PR</up>@)
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
FNC|microtubule-based movement ; GO:0007018 | inferred from electronic annotation
ENZ|GTPase activity ; GO:0003924 | inferred from electronic annotation
CEL|cytoplasm ; GO:0005737 | inferred from electronic annotation
}

REFDSR
{
RDID|FBrf0179435
|Schnorrer and Dickson
|2004
SYN|&bgr;1-Tubulin
}

REFDSR
{
RDID|FBrf0180120
|Inbal et al.
|2004
SYN|&bgr;1-tub
}

ALESR
{
ASYM|&bgr;Tub56D<up>EP2640</up>
ID|PFal0131824
REF|FBrf0132177
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0011303 == P{EP}&bgr;Tub56D<up>EP2640</up>
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0045841	CLA 1 engineered fusion gene ; SO:0000288	GSYM 1 &bgr;Tub56D::&bgr;Tub85D	DT 1 30 Oct 06	RESZ 459	REF 1	
GSYM|&bgr;Tub56D::&bgr;Tub85D
ID|PFgn0045841
CLA|engineered_fusion_gene ; SO:0000288
DT|30 Oct 06
REF
{
REFM|FBrf0136832
|Nielsen et al.
|2001
|-1
}

REFDSR
{
RDID|FBrf0136832
|Nielsen et al.
|2001
WTI|&bgr;Tub85D (data from @&bgr;Tub56D::&bgr;Tub85D<up>&bgr;1-&bgr;2.i</up>@, @&bgr;Tub56D::&bgr;Tub85D<up>&bgr;1-&bgr;2.iii</up>@, @&bgr;Tub56D::&bgr;Tub85D<up>&bgr;1-&bgr;2.iv</up>@)
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0003888	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &bgr;Tub60D	DT 1 30 Oct 06	RESZ 3700	FNC 1 microtubule-based process	CEL 2 microtubule	CLOC 1 60C6	ALESR 3	REF 17	
GSYM|&bgr;Tub60D
ID|PFgn0003888
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|77102
CLOC|60C6
|Limits computationally determined from genome sequence between @P{lacW}Nop60B<up>k05318</up>@ and @P{PZ}bs<up>03267</up>@&@P{lacW}l(2)k10502<up>k10502</up>@
FNC|microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from direct assay
|microtubule ; GO:0005874 | inferred from sequence or structural similarity
DT|30 Oct 06
REV|FBrf0151249
REF
{
REFM|FBrf0190767
|Ren et al.
|2005
|-1
REFM|FBrf0190293
|Hanson et al.
|2005
|-1
REFM|FBrf0132100
|Goldstein and Gunawardena
|2000
|-1
REFM|FBrf0188261
|Karlin et al.
|2005
|-1
REFM|FBrf0187296
|Baena-Lopez et al.
|2005
|-1
REFM|FBrf0052718
|Bruhat et al.
|1990
|-1
REFM|FBrf0167770
|Grevengoed et al.
|2003
|-1
REFM|FBrf0183733
|Mace and Tugores
|2004
|-1
REFM|FBrf0089630
|Dettman et al.
|1996
|-1
REFM|FBrf0191744
|Baena-Lopez
|2005
|-1
REFM|FBrf0189268
|Xu et al.
|2006
|-1
REFM|FBrf0187466
|Jin et al.
|2005
|-1
REFM|FBrf0187385
|Hebbar and Fernandes
|2005
|-1
REFM|FBrf0187384
|Fernandes et al.
|2005
|-1
REFM|FBrf0129830
|Goldstein and Gunawardena
|2000
|-1
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0187643
|Kristensen et al.
|2005
|-1
}

REFDSR
{
RDID|FBrf0129830
|Goldstein and Gunawardena
|2000
FNC|microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0132100
|Goldstein and Gunawardena
|2000
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
FNC|microtubule-based movement ; GO:0007018 | inferred from electronic annotation
ENZ|GTPase activity ; GO:0003924 | inferred from electronic annotation
}

REFDSR
{
RDID|FBrf0187643
|Kristensen et al.
|2005
SYN|143391_i_at
}

ALESR
{
ASYM|&bgr;Tub60D<up>2</up>
ID|PFal0000021
REF|FBrf0089630
REFDSR
{
RDID|FBrf0089630
|Dettman et al.
|1996
PHC|(with &bgr;Tub60D<up>P126</up>) lethal | pharate adult stage
}

}

ALESR
{
ASYM|&bgr;Tub60D<up>I-1.1.T:Ecol\CAT</up>
ID|PFal0055395
REF|FBrf0052718
REFDSR
{
RDID|FBrf0052718
|Bruhat et al.
|1990
OTH|Carried in plasmid "pTI-1.1", and transfected into Kc cells for transcriptional
|assays.
}

}

ALESR
{
ASYM|&bgr;Tub60D<up>I-4.5.T:Ecol\CAT</up>
ID|PFal0055394
REF|FBrf0052718
REFDSR
{
RDID|FBrf0052718
|Bruhat et al.
|1990
OTH|Carried in plasmid "pTI-4.5", and transfected into Kc cells for transcriptional
|assays.
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0015578	CLA 1 engineered fusion gene ; SO:0000288	GSYM 1 &bgr;Tub60D::&bgr;Tub85D	DT 1 30 Oct 06	RESZ 110	
GSYM|&bgr;Tub60D::&bgr;Tub85D
ID|PFgn0015578
CLA|engineered_fusion_gene ; SO:0000288
DT|30 Oct 06
}
# EOR
GENR
{
RETE|ID 1 PFgn0003889	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &bgr;Tub85D	DT 1 30 Oct 06	RESZ 4985	PDOM 5 INTERPRO:IPR000158 == Cell division protein FtsZ	FNC 1 microtubule-based process	CEL 1 microtubule	CLOC 1 85D15	ALESR 3	REF 15	
GSYM|&bgr;Tub85D
ID|PFgn0003889
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|107838
CLOC|85D15
|Limits computationally determined from genome sequence between @P{lacW}l(3)L4092<up>L4092</up>@ and P{PZ}ps<up>10615</up>&@P{PZ}Ras85D<up>06677</up>@
PDOM|IPR000158 == Cell division protein FtsZ
|IPR000217 == Tubulin
|IPR002453 == Beta tubulin
|IPR003008 == Tubulin/FtsZ, GTPase
|IPR008280 == Tubulin/FtsZ, C-terminal
FNC|microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0190293
|Hanson et al.
|2005
|-1
REFM|FBrf0132100
|Goldstein and Gunawardena
|2000
|-1
REFM|FBrf0188261
|Karlin et al.
|2005
|-1
REFM|FBrf0167770
|Grevengoed et al.
|2003
|-1
REFM|FBrf0136832
|Nielsen et al.
|2001
|-1
REFM|FBrf0189268
|Xu et al.
|2006
|-1
REFM|FBrf0034223
|Kemphues et al.
|1980
|-1
REFM|FBrf0187466
|Jin et al.
|2005
|-1
REFM|FBrf0189373
|Jafar-Nejad et al.
|2006
|-1
REFM|FBrf0137313
|Hoyle et al.
|2001
|-1
REFM|FBrf0132060
|Raff et al.
|2001
|-1
REFM|FBrf0129830
|Goldstein and Gunawardena
|2000
|-1
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0048424
|Fuller et al.
|1988
|-1
REFM|FBrf0078366
|Fackenthal et al.
|1995
|-1
}

REFDSR
{
RDID|FBrf0034223
|Kemphues et al.
|1980
GLOC|3-48.49
|Maps to the right of p: 0.5
}

REFDSR
{
RDID|FBrf0048424
|Fuller et al.
|1988
GLOC|Maps to the left of by
|Maps to the right of p
}

REFDSR
{
RDID|FBrf0078366
|Fackenthal et al.
|1995
WTI|&bgr;Tub60D::&bgr;Tub85D (data from @&bgr;Tub85D<up>3</up>@, @&bgr;Tub85D<up>6</up>@, @&bgr;Tub85D<up>7</up>@, @&bgr;Tub85D<up>8</up>@, @&bgr;Tub85D<up>Drv1</up>@)
}

REFDSR
{
RDID|FBrf0129830
|Goldstein and Gunawardena
|2000
FNC|microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0132060
|Raff et al.
|2001
WTI|&bgr;Tub56D (data from @&bgr;Tub85D<up>n</up>@)
}

REFDSR
{
RDID|FBrf0132100
|Goldstein and Gunawardena
|2000
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0136832
|Nielsen et al.
|2001
WTI|&bgr;Tub56D::&bgr;Tub85D (data from @&bgr;Tub85D<up>n</up>@)
}

REFDSR
{
RDID|FBrf0137313
|Hoyle et al.
|2001
WTI|&bgr;Tub60D::&bgr;Tub85D (data from @&bgr;Tub85D<up>432</up>@, @&bgr;Tub85D<up>n</up>@)
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
FNC|microtubule-based movement ; GO:0007018 | inferred from electronic annotation
|protein polymerization ; GO:0051258 | inferred from electronic annotation
ENZ|GTPase activity ; GO:0003924 | inferred from electronic annotation
CEL|cytoplasm ; GO:0005737 | inferred from electronic annotation
}

ALESR
{
ASYM|&bgr;Tub85D<up>432</up>
ID|PFal0028628
REF|FBrf0078366
REFDSR
{
RDID|FBrf0078366
|Fackenthal et al.
|1995
AMSO|Males carrying one copy of @P{B2t.432}@ in a hemizygous background
|(@&bgr;Tub85D<up>n</up>@/@&bgr;Tub85D@<up>+</up>) are sterile.
}

}

ALESR
{
ASYM|&bgr;Tub85D<up>6</up>
ID|PFal0000027
REF|FBrf0078366
REFDSR
{
RDID|FBrf0078366
|Fackenthal et al.
|1995
OTH|Class II allele. @P{&bgr;2&bgr;3*-pW8}@ and @&bgr;Tub85D<up>6</up>@ isoforms disrupt
|a common aspect of axoneme assembly.
}

}

ALESR
{
ASYM|&bgr;Tub85D<up>n</up>
ID|PFal0000036
REF|FBrf0048424
REFDSR
{
RDID|FBrf0048424
|Fuller et al.
|1988
PHC|(with &bgr;Tub85D<up>6</up>) male sterile
|(with &bgr;Tub85D<up>7</up>) male sterile
|(with &bgr;Tub85D<up>7</up>) meiotic | male
|(with &bgr;Tub85D<up>8</up>) male sterile
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0003890	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &bgr;Tub97EF	DT 1 30 Oct 06	RESZ 2638	FNC 6 cell motility	CEL 1 microtubule	CLOC 1 98B6--7	REF 11	
GSYM|&bgr;Tub97EF
ID|PFgn0003890
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|127194-8696
CLOC|98B6--7
|Limits computationally determined from genome sequence between @P{PZ}btz<up>rL203</up>@ and @P{PZ}l(3)06487<up>06487</up>@
FNC|cell motility ; GO:0006928 | inferred from electronic annotation
|chromosome segregation ; GO:0007059 | inferred from electronic annotation
|cytoskeleton organization and biogenesis ; GO:0007010 | inferred from electronic annotation
|intracellular protein transport ; GO:0006886 | inferred from electronic annotation
|microtubule-based movement ; GO:0007018 | inferred from electronic annotation
|mitosis ; GO:0007067 | inferred from electronic annotation
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0190767
|Ren et al.
|2005
|-1
REFM|FBrf0190293
|Hanson et al.
|2005
|-1
REFM|FBrf0132100
|Goldstein and Gunawardena
|2000
|-1
REFM|FBrf0188261
|Karlin et al.
|2005
|-1
REFM|FBrf0189751
|Liebl et al.
|2005
|-1
REFM|FBrf0167770
|Grevengoed et al.
|2003
|-1
REFM|FBrf0183733
|Mace and Tugores
|2004
|-1
REFM|FBrf0189268
|Xu et al.
|2006
|-1
REFM|FBrf0187466
|Jin et al.
|2005
|-1
REFM|FBrf0040719
|Natzle and McCarthy
|1984
|-1
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
}

REFDSR
{
RDID|FBrf0040719
|Natzle and McCarthy
|1984
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0132100
|Goldstein and Gunawardena
|2000
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
FNC|microtubule-based movement ; GO:0007018 | inferred from electronic annotation
ENZ|GTP binding ; GO:0005525 | inferred from electronic annotation
|GTPase activity ; GO:0003924 | inferred from electronic annotation
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0015000	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &bgr;ggt-I	DT 1 30 Oct 06	RESZ 1871	FNC 2 Ras protein signal transduction	CLOC 1 25B4	REF 4	
GSYM|&bgr;ggt-I
ID|PFgn0015000
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|34025
CLOC|25B4
|Limits computationally determined from genome sequence between @P{lacW}l(2)k10004<up>k10004</up>@&@P{EP}CG3036<up>EP963</up>@ and @P{PZ}l(2)05714<up>05714</up>@
FNC|Ras protein signal transduction ; GO:0007265 | inferred from sequence or structural similarity
|protein amino acid lipidation ; GO:0006497 | inferred from electronic annotation
ENZ|protein geranylgeranyltransferase activity ; GO:0004661 ; EC:2.5.1.- | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0086035
|Therrien et al.
|1995
|-1
REFM|FBrf0105879
|Maixner et al.
|1998
|-1
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
REFM|FBrf0161459
|Mi et al.
|2003.9.9
|-1
}

REFDSR
{
RDID|FBrf0086035
|Therrien et al.
|1995
ENZ|protein geranylgeranyltransferase activity ; GO:0004661 ; EC:2.5.1.- | inferred from sequence or structural similarity with EMBL:L25441; protein_id:AAA35888.1
|protein geranylgeranyltransferase activity ; GO:0004661 ; EC:2.5.1.- | inferred from sequence or structural similarity with EMBL:Z12155; protein_id:CAA78143.1
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
FNC|Ras protein signal transduction ; GO:0007265 | inferred from sequence or structural similarity with UniProt:P53610
ENZ|protein geranylgeranyltransferase activity ; GO:0004661 ; EC:2.5.1.- | inferred from sequence or structural similarity with UniProt:P53610
}

REFDSR
{
RDID|FBrf0105879
|Maixner et al.
|1998
WTI|sev (data from @&bgr;ggt-I<up>S-2554</up>@)
}

REFDSR
{
RDID|FBrf0161459
|Mi et al.
|2003.9.9
FNC|protein amino acid lipidation ; GO:0006497 | inferred from electronic annotation
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0028970	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &bgr;ggt-II	DT 1 30 Oct 06	RESZ 1040	FNC 1 protein amino acid lipidation	CLOC 1 23C1	REF 2	
GSYM|&bgr;ggt-II
ID|PFgn0028970
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|32182
CLOC|23C1
|Limits computationally determined from genome sequence between @P{PZ}oho23B<up>03575</up>@ and @P{PZ}lilli<up>00632</up>@
FNC|protein amino acid lipidation ; GO:0006497 | inferred from electronic annotation
DT|30 Oct 06
REF
{
REFM|FBrf0188255
|Cheng et al.
|2005
|-1
REFM|FBrf0161459
|Mi et al.
|2003.9.9
|-1
}

REFDSR
{
RDID|FBrf0161459
|Mi et al.
|2003.9.9
FNC|protein amino acid lipidation ; GO:0006497 | inferred from electronic annotation
}

REFDSR
{
RDID|FBrf0188255
|Cheng et al.
|2005
SYN|betaggt II
PHP|dsRNA made from templates generated with primers directed against @&bgr;ggt-II@
|that is transfected into S2 treated with Listeria monocytogenes reveals
|@&bgr;ggt-II@ to be involved in Listeria monocytogenes entry and vacuolar
|escape.
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0041583	CLA 1 gene ; SO:0000704	GSYM 1 &dgr;-catenin	DT 1 30 Oct 06	RESZ 296	CEL 1 zonula adherens	REF 1	
GSYM|&dgr;-catenin
ID|PFgn0041583
CLA|gene ; SO:0000704
CEL|zonula adherens ; GO:0005915 | non-traceable author statement
DT|30 Oct 06
REF
{
REFM|FBrf0189334
|Vidal et al.
|2006
|-1
}

REFDSR
{
RDID|FBrf0189334
|Vidal et al.
|2006
SYN|P120-catenin
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0028969	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &dgr;COP	DT 1 30 Oct 06	RESZ 3339	FNC 1 retrograde vesicle-mediated transport, Golgi to ER	CEL 2 COPI vesicle coat	CLOC 1 2B12--13	ALESR 1	REF 10	
GSYM|&dgr;COP
ID|PFgn0028969
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|1723-18013
CLOC|2B12--13
|Limits computationally determined from genome sequence between @P{EP}br<up>EP1515</up>@ and @P{EP}EP1444@&@P{EP}CG14818<up>EP1190</up>@
FNC|retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity
CEL|COPI vesicle coat ; GO:0030126 | inferred from sequence or structural similarity
|COPI vesicle coat ; GO:0030126 | non-traceable author statement
DT|30 Oct 06
REF
{
REFM|FBrf0107552
|Schaefer et al.
|1999.3.29
|-1
REFM|FBrf0187447
|Abrams and Andrew
|2005
|-1
REFM|-1032776461
|Hollien
|2006
|-1
|Science 313: http://www.sciencemag.org/cgi/content/full/313/5783/104/DC1
REFM|1376886708
|Zhang
|2006
|-1
|Proc. Natl. Acad. Sci. USA 103: 9357--9362
REFM|FBrf0190565
|Straub et al.
|2005
|-1
REFM|FBrf0190507
|Grieder et al.
|2005
|-1
REFM|FBrf0071734
|EDGP Project Members
|1994-
|-1
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0104946
|FlyBase
|1996-
|-1
}

REFDSR
{
RDID|FBrf0071734
|EDGP Project Members
|1994-
FNC|retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity
CEL|COPI vesicle coat ; GO:0030126 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0104946
|FlyBase
|1996-
AM|Source for merge of: &dgr;COP EG:63B12.10
|Source for merge of &dgr;COP EG:63B12.10 was sequence comparison (date:000202).
|Source for merge of: &dgr;COP anon-WO03040301.246
|Source for merge of &dgr;COP anon-WO03040301.246 was sequence comparison
|(date:051113).
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
FNC|retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity with UniProt:P53619
CEL|COPI vesicle coat ; GO:0030126 | inferred from sequence or structural similarity with UniProt:P53619
}

REFDSR
{
RDID|FBrf0107552
|Schaefer et al.
|1999.3.29
SYN|l(1)G0051
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
FNC|intracellular protein transport ; GO:0006886 | inferred from electronic annotation
CEL|clathrin vesicle coat ; GO:0030125 | inferred from electronic annotation
}

REFDSR
{
RDID|FBrf0187447
|Abrams and Andrew
|2005
MD|Identified with: GH18123
}

REFDSR
{
RDID|FBrf0190507
|Grieder et al.
|2005
MD|Identified with: GH18123
}

REFDSR
{
RDID|FBrf0190565
|Straub et al.
|2005
SYN|deltaCOP
}

REFDSR
{
RDID|1376886708
|Zhang
|2006
SYN|&dgr;COP
OTH|dsRNA made from templates generated with primers directed against this
|gene was tested in an RNAi screen to identify genes that regulate Ca<up>2+</up>
|release.
}

REFDSR
{
RDID|-1032776461
|Hollien
|2006
SYN|CG14813
}

ALESR
{
ASYM|&dgr;COP<up>G0051</up>
ID|PFal0096846
REF|FBrf0107552
REFDSR
{
RDID|FBrf0107552
|Schaefer et al.
|1999.3.29
SYN|l(1)G0051<up>G0051</up>
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0010358	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &dgr;Try	DT 1 30 Oct 06	RESZ 526	PDOM 1 INTERPRO:IPR001254 == Peptidase S1 and S6, chymotrypsin/Hap	FNC 1 proteolysis	CEL 1 extracellular region	CLOC 1 47F5	
GSYM|&dgr;Try
ID|PFgn0010358
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|59527
CLOC|47F5
|Limits computationally determined from genome sequence between @P{lacW}Fpps<up>k06103</up>@&@P{lacW}Fpps<up>k03514</up>@ and @P{lacW}Tap&dgr;<up>k17005</up>@&@P{lacW}k05103@
PDOM|IPR001254 == Peptidase S1 and S6, chymotrypsin/Hap
FNC|proteolysis ; GO:0006508 | non-traceable author statement
CEL|extracellular region ; GO:0005576 | non-traceable author statement
DT|30 Oct 06
}
# EOR
GENR
{
RETE|ID 1 PFgn0011554	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &eegr;Try	DT 1 30 Oct 06	RESZ 901	PDOM 2 INTERPRO:IPR001254 == Peptidase S1 and S6, chymotrypsin/Hap	FNC 1 proteolysis	CEL 1 extracellular region	CLOC 1 47F3	REF 1	
GSYM|&eegr;Try
ID|PFgn0011554
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|59495
CLOC|47F3
|Limits computationally determined from genome sequence between @P{lacW}Fpps<up>k06103</up>@&@P{lacW}Fpps<up>k03514</up>@ and @P{lacW}Tap&dgr;<up>k17005</up>@&@P{lacW}k05103@
PDOM|IPR001254 == Peptidase S1 and S6, chymotrypsin/Hap
|IPR009003 == Peptidase, trypsin-like serine and cysteine
FNC|proteolysis ; GO:0006508 | non-traceable author statement
ENZ|trypsin activity ; GO:0004295 ; EC:3.4.21.4 | inferred from sequence or structural similarity
CEL|extracellular region ; GO:0005576 | non-traceable author statement
DT|30 Oct 06
REF
{
REFM|FBrf0098301
|Louis et al.
|1997
|-1
}

REFDSR
{
RDID|FBrf0098301
|Louis et al.
|1997
ENZ|trypsin activity ; GO:0004295 ; EC:3.4.21.4 | inferred from sequence or structural similarity
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0027496	CLA 1 protein coding gene ; SO:0000010	NAM 1 &egr;COP	GSYM 1 &egr;COP	DT 1 30 Oct 06	RESZ 3584	PDOM 3 INTERPRO:IPR006822 == Coatomer epsilon subunit	DBA 10	FNC 2 intracellular protein transport	CEL 1 COPI vesicle coat	CLOC 1 26D9	ALESR 2	REF 8	
GSYM|&egr;COP
ID|PFgn0027496
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
NAM|&egr;COP
SYN|BcDNA:LD29885
|CG9543
KLOC|35621
CLOC|26D9
|Limits computationally determined from genome sequence between @P{EP}Sec61&agr;<up>EP2180</up>@ and @P{lacW}Ate1<up>k10809</up>@
UAB|Deficiency: In(2L)C263 (inferred from cytology)
|Duplication: Dp(2;2)C619 (inferred from cytology)
DBA|NA:AA949846
|BDGP-DGC:LD29885
|NA:AE003613
|PA:AAF52392
|NA:AF145691
|PA:AAD38666
|NA:AQ074039
|BDGP:EP(2)2027
|NA:AW942996
|BDGP-DGC:LD29885
PAC|UniProt:Q9Y0Y5
PDOM|IPR006822 == Coatomer epsilon subunit
|IPR008940 == Protein prenyltransferase
|IPR011990 == Tetratricopeptide-like helical
FNC|intracellular protein transport ; GO:0006886 | inferred from electronic annotation
|retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity
ENZ|binding ; GO:0005488 | inferred from electronic annotation
|protein transporter activity ; GO:0008565 | inferred from electronic annotation
CEL|COPI vesicle coat ; GO:0030126 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0166452
|Giot et al.
|2003
|-1
REFM|FBrf0187447
|Abrams and Andrew
|2005
|-1
REFM|FBrf0125078
|BDGP Project Members
|2000-
|-1
REFM|FBrf0132177
|Gene Disruption Project members
|2001-
|-1
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
REFM|FBrf0190507
|Grieder et al.
|2005
|-1
REFM|FBrf0161459
|Mi et al.
|2003.9.9
|-1
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
FNC|retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity with EMBL:U89427
CEL|COPI vesicle coat ; GO:0030126 | inferred from sequence or structural similarity with EMBL:U89427
}

REFDSR
{
RDID|FBrf0125078
|BDGP Project Members
|2000-
MD|Identified with: LD29885 (BDGP-DGC)
}

REFDSR
{
RDID|FBrf0161459
|Mi et al.
|2003.9.9
FNC|intracellular protein transport ; GO:0006886 | inferred from electronic annotation
}

REFDSR
{
RDID|FBrf0166452
|Giot et al.
|2003
SYN|BcDNA:LD29885
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
FNC|intracellular protein transport ; GO:0006886 | inferred from electronic annotation
ENZ|binding ; GO:0005488 | inferred from electronic annotation
|protein transporter activity ; GO:0008565 | inferred from electronic annotation
}

REFDSR
{
RDID|FBrf0187447
|Abrams and Andrew
|2005
MD|Identified with: LD29885
}

REFDSR
{
RDID|FBrf0190507
|Grieder et al.
|2005
AM|Source for identity of: &egr;COP CG9543
MD|Identified with: LD29885
}

ALESR
{
ASYM|&egr;COP<up>EP2027</up>
ID|PFal0131751
SYN|BcDNA:LD29885<up>EP2027</up>
|CG9543<up>EP2027</up>
REF|FBrf0132177
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
MU|P-element activity
TRN|FBti0010784 == P{EP}&egr;COP<up>EP2027</up>
}

}

ALESR
{
ASYM|&egr;COP<up>EY03980</up>
ID|PFal0156839
SYN|CG9543<up>EY03980</up>
REF|FBrf0132177
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
MU|P-element activity
TRN|FBti0027273 == P{EPgy2}&egr;COP<up>EY03980</up>
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0010425	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &egr;Try	DT 1 30 Oct 06	RESZ 656	PDOM 2 INTERPRO:IPR001254 == Peptidase S1 and S6, chymotrypsin/Hap	FNC 1 proteolysis	CEL 1 extracellular region	CLOC 1 47F4	REF 1	
GSYM|&egr;Try
ID|PFgn0010425
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|59509
CLOC|47F4
|Limits computationally determined from genome sequence between @P{lacW}Fpps<up>k06103</up>@&@P{lacW}Fpps<up>k03514</up>@ and @P{lacW}Tap&dgr;<up>k17005</up>@&@P{lacW}k05103@
PDOM|IPR001254 == Peptidase S1 and S6, chymotrypsin/Hap
|IPR009003 == Peptidase, trypsin-like serine and cysteine
FNC|proteolysis ; GO:0006508 | non-traceable author statement
CEL|extracellular region ; GO:0005576 | non-traceable author statement
DT|30 Oct 06
REF
{
REFM|FBrf0075304
|Hickey
|1993.9.2
|-1
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0028968	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &ggr;Cop	DT 1 30 Oct 06	RESZ 14585	DBA 7	FNC 2 cytokinesis	CEL 2 COPI vesicle coat	CLOC 1 100C6	ALESR 18	REF 20	
GSYM|&ggr;Cop
ID|PFgn0028968
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
ID2|FBgn0041590
SYN|l(3)S057302
|l(3)S057302b
KLOC|130168
CLOC|100C6
|Limits computationally determined from genome sequence between @P{PZ}l(3)rM731<up>rM731</up>@ and @P{EP}pygo<up>EP1076</up>@
DBA|NA:AY970668
|NA:DQ279401
|PA:ABB86288
|NA:DQ279402
|PA:ABB86289
|NA:DQ279403
|PA:ABB86290
PAC|UniProt:Q2VA12
FNC|cytokinesis ; GO:0000910 | inferred from mutant phenotype
|retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity
ENZ|binding ; GO:0005488 | inferred from electronic annotation
CEL|COPI vesicle coat ; GO:0030126 | inferred from sequence or structural similarity
|COPI vesicle coat ; GO:0030126 | non-traceable author statement
DT|30 Oct 06
REF
{
REFM|FBrf0115558
|Hahn
|1999.10.1
|-1
REFM|FBrf0191233
|Bjorklund et al.
|2006
|-1
REFM|2140598396
|GenBank/EMBL/DDBJ
|DQ279403
|-1
|GenBank/EMBL/DDBJ, DQ279403
REFM|FBrf0104946
|FlyBase
|1996-
|-1
REFM|FBrf0149093
|Johannes and Preiss
|2002
|-1
REFM|2140598394
|GenBank/EMBL/DDBJ
|DQ279402
|-1
|GenBank/EMBL/DDBJ, DQ279402
REFM|FBrf0188255
|Cheng et al.
|2005
|-1
REFM|2140598392
|GenBank/EMBL/DDBJ
|DQ279401
|-1
|GenBank/EMBL/DDBJ, DQ279401
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
REFM|FBrf0132177
|Gene Disruption Project members
|2001-
|-1
REFM|FBrf0191526
|Ecovoiu et al.
|2005
|-1
REFM|FBrf0191525
|Ecovoiu et al.
|2002
|-1
REFM|FBrf0190507
|Grieder et al.
|2005
|-1
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|-1032776461
|Hollien
|2006
|-1
|Science 313: http://www.sciencemag.org/cgi/content/full/313/5783/104/DC1
REFM|1989104088
|GenBank/EMBL/DDBJ
|AY970668
|-1
|GenBank/EMBL/DDBJ, AY970668
REFM|FBrf0187447
|Abrams and Andrew
|2005
|-1
REFM|FBrf0150040
|Davies
|2001.3.15
|-1
REFM|FBrf0099763
|Salzberg et al.
|1997
|-1
REFM|FBrf0099762
|Deak et al.
|1997
|-1
}

REFDSR
{
RDID|FBrf0099762
|Deak et al.
|1997
SYN|0573/02
}

REFDSR
{
RDID|FBrf0099763
|Salzberg et al.
|1997
SYN|573.02
GLOC|3-
}

REFDSR
{
RDID|FBrf0104946
|FlyBase
|1996-
AM|Source for merge of: &ggr;Cop anon-WO0118547.334
|Source for merge of &ggr;Cop anon-WO0118547.334 was sequence comparison
|(date:051113).
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
FNC|retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity with UniProt:P53620
CEL|COPI vesicle coat ; GO:0030126 | inferred from sequence or structural similarity with UniProt:P53620
}

REFDSR
{
RDID|FBrf0115558
|Hahn
|1999.10.1
FNC|retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | non-traceable author statement
}

REFDSR
{
RDID|FBrf0149093
|Johannes and Preiss
|2002
SYN|l(3)S057302
}

REFDSR
{
RDID|FBrf0150040
|Davies
|2001.3.15
OTH|Area matching Drosophila EST AA697891 (inverted). This EST has sequence similarity to Bovine gamma COP.
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
ENZ|binding ; GO:0005488 | inferred from electronic annotation
}

REFDSR
{
RDID|FBrf0187447
|Abrams and Andrew
|2005
MD|Identified with: RE62270
}

REFDSR
{
RDID|FBrf0188255
|Cheng et al.
|2005
PHP|dsRNA made from templates generated with primers directed against @&ggr;Cop@
|that is transfected into S2 treated with Listeria monocytogenes reveals
|@&ggr;Cop@ to be involved in Listeria monocytogenes entry and vacuolar
|escape.
}

REFDSR
{
RDID|FBrf0190507
|Grieder et al.
|2005
SYN|&ggr;COP
CLOC|100C (determined by in situ hybridization)
LOI|&ggr;Cop<up>A383.2M3</up>
MD|Identified with: LP01448
}

REFDSR
{
RDID|FBrf0191233
|Bjorklund et al.
|2006
SYN|&ggr;COP
}

REFDSR
{
RDID|FBrf0191525
|Ecovoiu et al.
|2002
AM|Source for merge of: &ggr;Cop l(3)S057302b
}

REFDSR
{
RDID|-1032776461
|Hollien
|2006
SYN|CG1528
}

ALESR
{
ASYM|&ggr;Cop<up>10a</up>
ID|PFal0900003
REF|FBrf0191526
REFDSR
{
RDID|FBrf0191526
|Ecovoiu et al.
|2005
MU|&Dgr;2-3
PRG|&ggr;Cop<up>S057302</up>
PHC|(with &ggr;Cop<up>S057302</up>) lethal
AFC|&ggr;Cop<up>S057302</up>
MD|Imprecise excision of the @P{lacW}@ element.
}

}

ALESR
{
ASYM|&ggr;Cop<up>11a</up>
ID|PFal0900004
DBA|NA:DQ279401
|PA:ABB86288
REF|FBrf0191526
|2140598392
REFDSR
{
RDID|FBrf0191526
|Ecovoiu et al.
|2005
MU|&Dgr;2-3
PRG|&ggr;Cop<up>S057302</up>
PHC|(with &ggr;Cop<up>S057302</up>) lethal
|viable
ALC|hypomorph
AFC|&ggr;Cop<up>S057302</up>
MD|Imprecise excision of the @P{lacW}@ element.
}

REFDSR
{
RDID|2140598392
|GenBank/EMBL/DDBJ
|DQ279401
TRN|P{?lacW}&ggr;Cop<up>11a</up>
ALC|hypomorph
}

}

ALESR
{
ASYM|&ggr;Cop<up>14a</up>
ID|PFal0900005
DBA|NA:DQ279402
|PA:ABB86289
REF|FBrf0191526
|2140598394
REFDSR
{
RDID|FBrf0191526
|Ecovoiu et al.
|2005
MU|&Dgr;2-3
PRG|&ggr;Cop<up>S057302</up>
PHC|(with &ggr;Cop<up>S057302</up>) lethal
ALC|hypomorph
AFC|&ggr;Cop<up>S057302</up>
MD|Imprecise excision of the @P{lacW}@ element.
}

REFDSR
{
RDID|2140598394
|GenBank/EMBL/DDBJ
|DQ279402
TRN|P{?lacW}&ggr;Cop<up>14a</up>
ALC|hypomorph
}

}

ALESR
{
ASYM|&ggr;Cop<up>15a</up>
ID|PFal0900006
REF|FBrf0191526
REFDSR
{
RDID|FBrf0191526
|Ecovoiu et al.
|2005
MU|&Dgr;2-3
PRG|&ggr;Cop<up>S057302</up>
PHC|(with &ggr;Cop<up>S057302</up>) lethal
ALC|hypomorph
AFC|&ggr;Cop<up>S057302</up>
MD|Imprecise excision of the @P{lacW}@ element.
}

}

ALESR
{
ASYM|&ggr;Cop<up>16a</up>
ID|PFal0900007
REF|FBrf0191526
REFDSR
{
RDID|FBrf0191526
|Ecovoiu et al.
|2005
MU|&Dgr;2-3
PRG|&ggr;Cop<up>S057302</up>
PHC|(with &ggr;Cop<up>S057302</up>) lethal
AFC|&ggr;Cop<up>S057302</up>
MD|Imprecise excision of the @P{lacW}@ element.
}

}

ALESR
{
ASYM|&ggr;Cop<up>16b</up>
ID|PFal0900008
DBA|NA:DQ279403
|PA:ABB86290
REF|FBrf0191526
|2140598396
REFDSR
{
RDID|FBrf0191526
|Ecovoiu et al.
|2005
MU|&Dgr;2-3
PRG|&ggr;Cop<up>S057302</up>
PHC|(with &ggr;Cop<up>S057302</up>) lethal
ALC|hypomorph
AFC|&ggr;Cop<up>S057302</up>
MD|Imprecise excision of the @P{lacW}@ element.
}

REFDSR
{
RDID|2140598396
|GenBank/EMBL/DDBJ
|DQ279403
TRN|P{?lacW}&ggr;Cop<up>16b</up>
ALC|hypomorph
}

}

ALESR
{
ASYM|&ggr;Cop<up>17b</up>
ID|PFal0900009
REF|FBrf0191526
REFDSR
{
RDID|FBrf0191526
|Ecovoiu et al.
|2005
MU|&Dgr;2-3
PRG|&ggr;Cop<up>S057302</up>
PHC|(with &ggr;Cop<up>S057302</up>) lethal
AFC|&ggr;Cop<up>S057302</up>
MD|Imprecise excision of the @P{lacW}@ element.
}

}

ALESR
{
ASYM|&ggr;Cop<up>1b</up>
ID|PFal0900010
REF|FBrf0191526
REFDSR
{
RDID|FBrf0191526
|Ecovoiu et al.
|2005
MU|&Dgr;2-3
PRG|&ggr;Cop<up>S057302</up>
PHC|(with &ggr;Cop<up>S057302</up>) lethal
AFC|&ggr;Cop<up>S057302</up>
MD|Imprecise excision of the @P{lacW}@ element.
}

}

ALESR
{
ASYM|&ggr;Cop<up>20b</up>
ID|PFal0900011
REF|FBrf0191526
REFDSR
{
RDID|FBrf0191526
|Ecovoiu et al.
|2005
MU|&Dgr;2-3
PRG|&ggr;Cop<up>S057302</up>
PHC|(with &ggr;Cop<up>S057302</up>) lethal
AFC|&ggr;Cop<up>S057302</up>
MD|Imprecise excision of the @P{lacW}@ element.
}

}

ALESR
{
ASYM|&ggr;Cop<up>21b</up>
ID|PFal0900012
REF|FBrf0191526
REFDSR
{
RDID|FBrf0191526
|Ecovoiu et al.
|2005
MU|&Dgr;2-3
PRG|&ggr;Cop<up>S057302</up>
PHC|(with &ggr;Cop<up>S057302</up>) lethal
AFC|&ggr;Cop<up>S057302</up>
MD|Imprecise excision of the @P{lacW}@ element.
}

}

ALESR
{
ASYM|&ggr;Cop<up>5a</up>
ID|PFal0900013
REF|FBrf0191526
REFDSR
{
RDID|FBrf0191526
|Ecovoiu et al.
|2005
MU|&Dgr;2-3
PRG|&ggr;Cop<up>S057302</up>
PHC|(with &ggr;Cop<up>S057302</up>) lethal
AFC|&ggr;Cop<up>S057302</up>
MD|Imprecise excision of the @P{lacW}@ element.
}

}

ALESR
{
ASYM|&ggr;Cop<up>6a</up>
ID|PFal0900014
REF|FBrf0191526
REFDSR
{
RDID|FBrf0191526
|Ecovoiu et al.
|2005
MU|&Dgr;2-3
PRG|&ggr;Cop<up>S057302</up>
PHC|(with &ggr;Cop<up>S057302</up>) lethal
AFC|&ggr;Cop<up>S057302</up>
MD|Imprecise excision of the @P{lacW}@ element.
}

}

ALESR
{
ASYM|&ggr;Cop<up>7a</up>
ID|PFal0900015
REF|FBrf0191526
REFDSR
{
RDID|FBrf0191526
|Ecovoiu et al.
|2005
MU|&Dgr;2-3
PRG|&ggr;Cop<up>S057302</up>
PHC|(with &ggr;Cop<up>S057302</up>) lethal
AFC|&ggr;Cop<up>S057302</up>
MD|Imprecise excision of the @P{lacW}@ element.
}

}

ALESR
{
ASYM|&ggr;Cop<up>8a</up>
ID|PFal0900016
REF|FBrf0191526
REFDSR
{
RDID|FBrf0191526
|Ecovoiu et al.
|2005
MU|&Dgr;2-3
PRG|&ggr;Cop<up>S057302</up>
PHC|(with &ggr;Cop<up>S057302</up>) lethal
AFC|&ggr;Cop<up>S057302</up>
MD|Imprecise excision of the @P{lacW}@ element.
}

}

ALESR
{
ASYM|&ggr;Cop<up>9a</up>
ID|PFal0900017
REF|FBrf0191526
REFDSR
{
RDID|FBrf0191526
|Ecovoiu et al.
|2005
MU|&Dgr;2-3
PRG|&ggr;Cop<up>S057302</up>
PHC|(with &ggr;Cop<up>S057302</up>) lethal
AFC|&ggr;Cop<up>S057302</up>
MD|Imprecise excision of the @P{lacW}@ element.
}

}

ALESR
{
ASYM|&ggr;Cop<up>A383.2M3</up>
ID|PFal0900018
DBA|NA:AY970668
REF|1989104088
|FBrf0190507
REFDSR
{
RDID|FBrf0190507
|Grieder et al.
|2005
AMIS|Separable from: a separable lethal mutation.
TRN|P{lArB}&ggr;Cop<up>A383.2M3</up>
PHC|fertile
|viable
MD|@P{lArB}@ insertion within the 5' UTR.
}

REFDSR
{
RDID|1989104088
|GenBank/EMBL/DDBJ
|AY970668
TRN|P{lArB}&ggr;Cop<up>A383.2M3</up>
}

}

ALESR
{
ASYM|&ggr;Cop<up>KG06383</up>
ID|PFal0137678
REF|FBrf0132177
REFDSR
{
RDID|FBrf0132177
|Gene Disruption Project members
|2001-
TRN|FBti0023545 == P{SUPor-P}&ggr;Cop<up>KG06383</up>
}

}

ALESR
{
ASYM|&ggr;Cop<up>S057302</up>
ID|PFal0137677
ID2|FBal0105011
SYN|&ggr;Cop<up>S057302a</up>
|l(3)S057302<up>S057302</up>
|l(3)S057302b<up>S057302b</up>
MU|P-element activity
TRN|FBti0010597 == P{lacW}&ggr;Cop<up>S057302</up>
DBA|NA:AJ492220
REF|FBrf0099762
|FBrf0191525
|FBrf0191526
|FBrf0149093
|FBrf0099763
REFDSR
{
RDID|FBrf0099762
|Deak et al.
|1997
SYN|0573/02
MU|&Dgr;2-3
PHC|lethal | recessive
PHI|Early lethal.
}

REFDSR
{
RDID|FBrf0099763
|Salzberg et al.
|1997
SYN|573.02
MU|P-element activity
PHC|lethal | embryonic stage | recessive
PHM|embryonic nervous system
OTH|Reversion analysis demonstrates the insertion may not be
|responsible for the lethal phenotype.
}

REFDSR
{
RDID|FBrf0149093
|Johannes and Preiss
|2002
SYN|l(3)S057302<up>S057302</up>
}

REFDSR
{
RDID|FBrf0191525
|Ecovoiu et al.
|2002
TRN|FBti0010597 == P{lacW}&ggr;Cop<up>S057302</up>
PHC|lethal | recessive
OTH|Precise excision of the @P{lacW}@ insertion can revert the lethal phenotype,
|indicating that the P{lacW}&ggr;Cop<up>S057302</up> insertion within the
|@&ggr;Cop@ gene is responsible for the homozygous lethality of the
|"l(3)S057302" chromosome.
}

REFDSR
{
RDID|FBrf0191526
|Ecovoiu et al.
|2005
TRN|FBti0010597 == P{lacW}&ggr;Cop<up>S057302</up>
PHC|(with &ggr;Cop<up>10a</up>) lethal
|(with &ggr;Cop<up>11a</up>) lethal
|(with &ggr;Cop<up>14a</up>) lethal
|(with &ggr;Cop<up>15a</up>) lethal
|(with &ggr;Cop<up>16a</up>) lethal
|(with &ggr;Cop<up>16b</up>) lethal
|(with &ggr;Cop<up>17b</up>) lethal
|(with &ggr;Cop<up>1b</up>) lethal
|(with &ggr;Cop<up>20b</up>) lethal
|(with &ggr;Cop<up>21b</up>) lethal
|(with &ggr;Cop<up>5a</up>) lethal
|(with &ggr;Cop<up>6a</up>) lethal
|(with &ggr;Cop<up>7a</up>) lethal
|(with &ggr;Cop<up>8a</up>) lethal
|(with &ggr;Cop<up>9a</up>) lethal
AFC|&ggr;Cop<up>10a</up>
|&ggr;Cop<up>11a</up>
|&ggr;Cop<up>14a</up>
|&ggr;Cop<up>15a</up>
|&ggr;Cop<up>16a</up>
|&ggr;Cop<up>16b</up>
|&ggr;Cop<up>17b</up>
|&ggr;Cop<up>1b</up>
|&ggr;Cop<up>20b</up>
|&ggr;Cop<up>21b</up>
|&ggr;Cop<up>5a</up>
|&ggr;Cop<up>6a</up>
|&ggr;Cop<up>7a</up>
|&ggr;Cop<up>8a</up>
|&ggr;Cop<up>9a</up>
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0028552	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &ggr;Snap	DT 1 30 Oct 06	RESZ 1076	PDOM 1 INTERPRO:IPR000744 == NSF attachment protein	FNC 2 neurotransmitter secretion	CEL 1 cytoplasm	CLOC 1 60B5	REF 1	
GSYM|&ggr;Snap
ID|PFgn0028552
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|76751
CLOC|60B5
|Limits computationally determined from genome sequence between @P{lacW}Phm<up>k07623</up>@&@P{lacW}tsr<up>k05633</up>@ and @P{EP}EP503@
PDOM|IPR000744 == NSF attachment protein
FNC|neurotransmitter secretion ; GO:0007269 | non-traceable author statement
|synaptic vesicle priming ; GO:0016082 | non-traceable author statement
ENZ|binding ; GO:0005488 | inferred from electronic annotation
CEL|cytoplasm ; GO:0005737 | non-traceable author statement
DT|30 Oct 06
REF
{
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
FNC|intracellular protein transport ; GO:0006886 | inferred from electronic annotation
ENZ|binding ; GO:0005488 | inferred from electronic annotation
CEL|Golgi apparatus ; GO:0005794 | inferred from electronic annotation
|endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0043017	CLA 1 gene ; SO:0000704	GSYM 1 &ggr;Snap-2	DT 1 30 Oct 06	RESZ 288	FNC 2 neurotransmitter secretion	CEL 1 cytoplasm	
GSYM|&ggr;Snap-2
ID|PFgn0043017
CLA|gene ; SO:0000704
FNC|neurotransmitter secretion ; GO:0007269 | non-traceable author statement
|synaptic vesicle priming ; GO:0016082 | non-traceable author statement
CEL|cytoplasm ; GO:0005737 | non-traceable author statement
DT|30 Oct 06
}
# EOR
GENR
{
RETE|ID 1 PFgn0010359	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &ggr;Try	DT 1 30 Oct 06	RESZ 891	CLOC 1 47F4	REF 2	
GSYM|&ggr;Try
ID|PFgn0010359
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|59509
CLOC|47F4
|Limits computationally determined from genome sequence between @P{lacW}Fpps<up>k06103</up>@&@P{lacW}Fpps<up>k03514</up>@ and @P{lacW}Tap&dgr;<up>k17005</up>@&@P{lacW}k05103@
ENZ|NOT serine-type endopeptidase activity ; GO:0004252 ; EC:3.4.21 | non-traceable author statement
DT|30 Oct 06
REF
{
REFM|FBrf0104946
|FlyBase
|1996-
|-1
REFM|FBrf0155784
|Ross et al.
|2003
|-1
}

REFDSR
{
RDID|FBrf0104946
|FlyBase
|1996-
AM|Source for merge of: &ggr;Try BcDNA:RE40325
|Source for merge of &ggr;Try BcDNA:RE40325 was a shared cDNA (date:030728).
}

REFDSR
{
RDID|FBrf0155784
|Ross et al.
|2003
ENZ|NOT serine-type endopeptidase activity ; GO:0004252 ; EC:3.4.21 | non-traceable author statement
}

}
# EOR
GENR
{
RETE|ID 1 PFgn0004176	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &ggr;Tub23C	DT 1 30 Oct 06	RESZ 6118	FNC 2 microtubule-based process	CEL 3 gamma-tubulin small complex	CLOC 1 23C4	ALESR 2	REF 23	
GSYM|&ggr;Tub23C
ID|PFgn0004176
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|32251
CLOC|23C4
|Limits computationally determined from genome sequence between @P{PZ}lilli<up>00632</up>@ and @P{PZ}toc<up>01361</up>@
FNC|microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity
|microtubule-based process ; GO:0007017 | non-traceable author statement
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|gamma-tubulin small complex ; GO:0008275 | inferred from sequence or structural similarity
|microtubule ; GO:0005874 | inferred from sequence or structural similarity
|microtubule organizing center ; GO:0005815 | inferred from sequence or structural similarity
DT|30 Oct 06
REF
{
REFM|FBrf0189137
|Vazquez et al.
|2006
|-1
REFM|FBrf0132100
|Goldstein and Gunawardena
|2000
|-1
REFM|-809837969
|M Mahoney
|2006
|-1
|Curr. Biol. 16: http://www.current-biology.com/cgi/content/full/16/6/564/DC1/
REFM|FBrf0190017
|Goshima et al.
|2005
|-1
REFM|FBrf0189924
|Siegrist and Doe
|2005
|-1
REFM|FBrf0179327
|Martinez-Campos et al.
|2004
|-1
REFM|FBrf0189056
|Brill et al.
|2006
|-1
REFM|-615930925
|Basto
|2006
|-1
|Cell 125: 1375--1386
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
REFM|FBrf0167770
|Grevengoed et al.
|2003
|-1
REFM|FBrf0129830
|Goldstein and Gunawardena
|2000
|-1
REFM|FBrf0189998
|Bettencourt-Dias et al.
|2005
|-1
REFM|FBrf0191755
|Bettencourt-Dias et al.
|2005
|-1
REFM|FBrf0189549
|Zhang and Megraw
|2006
|-1
REFM|FBrf0187387
|Kai et al.
|2005
|-1
REFM|FBrf0174805
|Butcher et al.
|2004
|-1
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0188261
|Karlin et al.
|2005
|-1
REFM|FBrf0184171
|Bettencourt-Dias et al.
|2004
|-1
REFM|FBrf0187336
|Stumpff et al.
|2005
|-1
REFM|FBrf0187303
|Chodagam et al.
|2005
|-1
REFM|FBrf0161562
|Yamashita et al.
|2003
|-1
REFM|FBrf0187226
|Emery et al.
|2005
|-1
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity with UniProt:P23330
CEL|gamma-tubulin small complex ; GO:0008275 | inferred from sequence or structural similarity with UniProt:P23330
|microtubule ; GO:0005874 | inferred from sequence or structural similarity with UniProt:P23330
|microtubule organizing center ; GO:0005815 | inferred from sequence or structural similarity with UniProt:P23330
}

REFDSR
{
RDID|FBrf0129830
|Goldstein and Gunawardena
|2000
FNC|microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0132100
|Goldstein and Gunawardena
|2000
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0174215
|FlyBase Curators et al.
|2004-
FNC|microtubule-based movement ; GO:0007018 | inferred from electronic annotation
ENZ|GTPase activity ; GO:0003924 | inferred from electronic annotation
}

REFDSR
{
RDID|FBrf0179327
|Martinez-Campos et al.
|2004
SYN|GTU88*
}

REFDSR
{
RDID|FBrf0184171
|Bettencourt-Dias et al.
|2004
SYN|&ggr;-tubulin
}

REFDSR
{
RDID|FBrf0187387
|Kai et al.
|2005
SYN|&ggr;-Tub23C
}

REFDSR
{
RDID|FBrf0189137
|Vazquez et al.
|2006
WTI|N
|brm
}

REFDSR
{
RDID|FBrf0189549
|Zhang and Megraw
|2006
SYN|gamma tubulin
}

REFDSR
{
RDID|FBrf0187226
|Emery et al.
|2005
SYN|&ggr;Tub
}

REFDSR
{
RDID|-809837969
|M Mahoney
|2006
SYN|CG 3157
FNC|microtubule nucleation ; GO:0007020 | inferred from mutant phenotype
}

REFDSR
{
RDID|-615930925
|Basto
|2006
SYN|GTU88*
}

ALESR
{
ASYM|&ggr;Tub23C<up>2</up>
ID|PFal0900019
REF|FBrf0189137
REFDSR
{
RDID|FBrf0189137
|Vazquez et al.
|2006
SYN|Pl[2]
PHC|visible | dominant
PHM|eye
|wing
|wing blade
|wing vein
PHI|Heterozygotes have small eyes, held-out and notched wings, wing
|blisters and pearl-like structures in the wing blade and veins.
}

}

ALESR
{
ASYM|&ggr;Tub23C<up>dsRNA.cMa</up>
ID|PFal0900020
REF|-809837969
REFDSR
{
RDID|-809837969
|M Mahoney
|2006
MU|in vitro construct | RNAi
PHM|spindle
PHI|@&ggr;Tub23C<up>dsRNA.cMa</up>@-treated S2 cells display a relative mitotic
|index 3.3-fold that of untreated cells, which is considered statistically
|significant.
|Approximately 38% of @&ggr;Tub23C<up>dsRNA.cMa</up>@-treated mitotic S2 cells
|display monopolar spindles, approximately 60% exhibit anastral spindles.
|Mode of assay: Drosophila cell culture
OTH|dsRNA has been synthesised from the template and used to treat S2 cells
|to study the phenotypic consequences of dsRNA interference (RNAi) of
|the @&ggr;Tub23C@ gene.
}

}

}
# EOR
GENR
{
RETE|ID 1 PFgn0010097	CLA 1 protein coding gene ; SO:0000010	GSYM 1 &ggr;Tub37C	DT 1 30 Oct 06	RESZ 5770	FNC 2 microtubule-based process	CEL 2 microtubule	CLOC 1 37C7	ALESR 3	REF 18	
GSYM|&ggr;Tub37C
ID|PFgn0010097
CLA|protein_coding_gene ; SO:0000010
|nuclear_gene ; SO:0000087
|protein_coding_gene ; SO:0000010
KLOC|46853
CLOC|37C7
|Limits computationally determined from genome sequence between @P{lacW}brat<up>k06028</up>@&@P{lacW}l(2)k09613<up>k09613</up>@ and @P{EP}dnt<up>EP2158</up>@
FNC|microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity
|microtubule-based process ; GO:0007017 | non-traceable author statement
ENZ|structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
|microtubule organizing center ; GO:0005815 | inferred from sequence or structural similarity
DT|30 Oct 06
OTH|Identification: Saturation mutagenesis of @Df(2L)TW130@.
REF
{
REFM|FBrf0132100
|Goldstein and Gunawardena
|2000
|-1
REFM|FBrf0187222
|Delanoue and Davis
|2005
|-1
REFM|-809837969
|M Mahoney
|2006
|-1
|Curr. Biol. 16: http://www.current-biology.com/cgi/content/full/16/6/564/DC1/
REFM|FBrf0083785
|Bolwig et al.
|1995
|-1
REFM|FBrf0179327
|Martinez-Campos et al.
|2004
|-1
REFM|FBrf0187140
|McGregor
|2005
|-1
REFM|FBrf0105495
|FlyBase
|FlyBase analysis
|-1
REFM|FBrf0167770
|Grevengoed et al.
|2003
|-1
REFM|FBrf0129830
|Goldstein and Gunawardena
|2000
|-1
REFM|FBrf0189549
|Zhang and Megraw
|2006
|-1
REFM|FBrf0174805
|Butcher et al.
|2004
|-1
REFM|FBrf0174215
|FlyBase Curators et al.
|2004-
|-1
REFM|FBrf0167369
|Ephrussi and St. Johnston
|2004
|-1
REFM|FBrf0188261
|Karlin et al.
|2005
|-1
REFM|FBrf0118617
|Oakley
|1991.10.4
|-1
REFM|FBrf0184171
|Bettencourt-Dias et al.
|2004
|-1
REFM|FBrf0187336
|Stumpff et al.
|2005
|-1
REFM|FBrf0187303
|Chodagam et al.
|2005
|-1
}

REFDSR
{
RDID|FBrf0083785
|Bolwig et al.
|1995
MD|Gene order: In direction of increasing cytology: &ggr;Tub37C? pigeon+ drl+
}

REFDSR
{
RDID|FBrf0105495
|FlyBase
|FlyBase analysis
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity with UniProt:P23330
}

REFDSR
{
RDID|FBrf0118617
|Oakley
|1991.10.4
CEL|microtubule ; GO:0005874 | inferred from sequence or structural similarity
|microtubule organizing center ; GO:0005815 | inferred from sequence or structural similarity
}

REFDSR
{
RDID|FBrf0129830
|Goldstein and Gunawardena
|2000
FNC|microtubule-based process ; GO:0007017 | inferred from sequence or structu